Correlation between venous blood gas indices and radiological involvements of COVID-19 patients at first admission to emergency department.

Autor: Dheir H; Sakarya University, Faculty of Medicine, Division of Nephrology - Sakarya, Turquia., Karacan A; Sakarya University, Faculty of Medicine, Department of Radiology - Sakarya, Turquia., Sipahi S; Sakarya University, Faculty of Medicine, Division of Nephrology - Sakarya, Turquia., Yaylaci S; Sakarya University, Faculty of Medicine, Department of Internal Medicine - Sakarya, Turquia., Tocoglu A; Sakarya University, Faculty of Medicine, Department of Internal Medicine - Sakarya, Turquia., Demirci T; Sakarya University, Faculty of Medicine, Division of Endocrinology and Metabolism - Sakarya, Turquia., Cetin ES; Sakarya University, Faculty of Medicine, Department of Internal Medicine - Sakarya, Turquia., Guneysu F; Sakarya University, Faculty of Medicine, Department of Emergency - Sakarya, Turquia., Firat N; Sakarya University, Faculty of Medicine, Department of General Surgery - Sakarya, Turquia., Varim C; Sakarya University, Faculty of Medicine, Department of Internal Medicine - Sakarya, Turquia., Karabay O; Sakarya University, Faculty of Medicine, Department of Infectious Diseases and Microbiology - Sakarya, Turquia.
Jazyk: angličtina
Zdroj: Revista da Associacao Medica Brasileira (1992) [Rev Assoc Med Bras (1992)] 2021 Aug 13; Vol. 67Suppl 1 (Suppl 1), pp. 51-56. Date of Electronic Publication: 2021 Aug 13 (Print Publication: 2021).
DOI: 10.1590/1806-9282.67.Suppl1.20200715
Abstrakt: Background: The purpose of this study was to investigate the relation between venous blood gas and chest computerized tomography findings and the clinical conditions of COVID-19 pneumonia.
Methods: A total of 309 patients admitted to the emergency department and subsequently confirmed COVID-19 cases was examined. Patients with pneumonia symptoms, chest computerized tomography scan, venous blood gas findings, and confirmed COVID-19 on reverse transcription-polymerase chain reaction (PCR) were consecutively enrolled. Multiple linear regression was used to predict computerized tomography and blood gas findings by clinical/laboratory data.
Results: The median age of patients was 51 (interquartile range 39-66), and 51.5% were male. The mortality rate at the end of follow-up was 18.8%. With respect to survival status of patients pCO2 and HCO3 levels and total computerized tomography score values were found to be higher in the surviving patients (p<0.001 and p=0.003, respectively), whereas pH and lactate levels were higher in patients who died (p=0.022 and p=0.001, respectively). With logistic regression analysis, total tomography score was found to be significantly effective on mortality (p<0.001). The diffuse and random involvement of the lungs had a significant effect on mortality (p<0.001, 95%CI 3.853-38.769, OR 12.222 and p=0.027; 95%CI 1.155-11.640, OR 3.667, respectively). With linear regression analysis, the effect of pH and lactate results were found to have a positive effect on total tomography score (p=0.003 and p<0.001, respectively), whereas pCO2 was found to have a negative effect (p=0.029).
Conclusion: There was correlation between venous blood gas indices and radiologic scores in COVID-19 patients. Venous blood gas taken in emergency department can be a fast, applicable, minor-invasive, and complementary test in terms of diagnosing COVID-19 pneumonia and predicting the prognosis of disease.
Databáze: MEDLINE