[Surgical and combined treatment of patients with duodenal stromal tumors].

Autor:	Arkhiri PP; Blokhin National Cancer Research Center, Moscow, Russia.; Russian Medical Academy of Continuous Professional Education, Moscow, Russia., Stilidi IS; Blokhin National Cancer Research Center, Moscow, Russia.; Russian Medical Academy of Continuous Professional Education, Moscow, Russia., Nered SN; Blokhin National Cancer Research Center, Moscow, Russia.; Russian Medical Academy of Continuous Professional Education, Moscow, Russia., Abgaryan MG; Blokhin National Cancer Research Center, Moscow, Russia., Nikulin MP; Blokhin National Cancer Research Center, Moscow, Russia., Meshcheryakov AA; Blokhin National Cancer Research Center, Moscow, Russia., Filonenko DA; Blokhin National Cancer Research Center, Moscow, Russia., Egenov OA; Blokhin National Cancer Research Center, Moscow, Russia., Yugai VV; Blokhin National Cancer Research Center, Moscow, Russia., Volkov AY; Blokhin National Cancer Research Center, Moscow, Russia.
Jazyk:	English; Russian
Zdroj:	Khirurgiia [Khirurgiia (Mosk)] 2021 (8), pp. 11-19.
DOI:	10.17116/hirurgia202108111
Abstrakt:	Objective: To evaluate the immediate and long-term results of surgical and combined treatment of patients with duodenal stromal tumors. Material and Methods: There were 47 patients with duodenal stromal tumors for the period 2002-2019. All patients underwent treatment at the Blokhin National Cancer Research Center. Six patients had metastatic disease, 2 ones - a rare syndrome of duodenal stromal tumor associated with neurofibromatosis type 1, other 39 patients had a localized and locally-advanced disease. Surgical treatment was performed in 37 patients (limited resections (LR) in 24 cases and gastropancreaticoduodenectomy in 13 cases). Incidence of postoperative complications was significantly lower after limited resections compared to gastropancreaticoduodenectomy (22.2% (6/24) vs. 61.5% (8/13), respectively). Severe complications (Clavien-Dindo grade 3) occurred in 4.2% (1/24) vs. 15.3% (2/13) of patients, respectively. Postoperative mortality was absent in both groups. We observed no significant differences in long-term results. Overall 5-year survival was 91% and 70% ( p =0.5960), 5-year recurrence-free survival - 65 and 70% ( p =0.6226), respectively. Conclusion: Considering similar survival rates, lower postoperative morbidity and better quality of life, limited duodenal resections are preferred for duodenal stromal tumors.
Databáze:	MEDLINE
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