Clinical and etiological profile of epilepsy at the regional hospital center of Tahoua (Niger): A 4-year retrospective study.

Autor: Toudou-Daouda M; Department of Neurology, National Hospital of Niamey, Niamey, Niger., Ibrahim-Mamadou AK; Department of Medicine and Medical Specialties, Regional Hospital Center of Tahoua, Tahoua, Niger.
Jazyk: angličtina
Zdroj: Brain and behavior [Brain Behav] 2021 Aug; Vol. 11 (8), pp. e2301. Date of Electronic Publication: 2021 Jul 21.
DOI: 10.1002/brb3.2301
Abstrakt: Objective: We aimed to evaluate epilepsy management at the regional hospital center (RHC) of Tahoua (Niger) to determine the intrahospital deficiencies to optimize to improve the management of people with epilepsy.
Methods: A descriptive retrospective study was carried out at the Psychiatric Unit of the RHC of Tahoua between January 1, 2016 and December 31, 2019. We collected from the registers of consultation all patients followed by nurse technicians in mental health for epilepsy whose diagnosis was made by nonspecialist physicians or internists. The study included patients with epilepsy who had a medical follow-up at least 6 months.
Results: Of the 2022 patients seen during the period of the study, 246 patients were consulted for epilepsy with a hospital frequency of 12.2%. The mean age was 22.38 years, with a slight predominance of men (57.7%). Only generalized tonic-clonic seizures (95.1%) and focal-aware seizures (4.9%) were reported. The main etiologies were cerebral malaria (18.7%), bacterial meningitis (8.1%), and head trauma (4.9%). In 60.2% of cases, the etiology was undetermined, but the etiological diagnosis investigation was incomplete (CT scan not done). Only the first-generation antiepileptic drugs were used. Only 2.8% of the patients had drug-resistant epilepsy, and 97.2% of the patients had controlled seizures.
Conclusion: The study shows a predominance of infectious causes, particularly cerebral malaria. We found a high proportion of epilepsies with unknown etiologies with incomplete workup. The RHC of Tahoua should facilitate access to the CT scan for people with epilepsy to improve etiological diagnosis investigation.
(© 2021 The Authors. Brain and Behavior published by Wiley Periodicals LLC.)
Databáze: MEDLINE
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