Symptomatic Chiari type 1 malformation associated with acromegaly: A case report.
| Autor: | Aoki T; Department of Neurosurgery, Saiseikai Shiga Hospital, Ritto, Japan., Umebayashi D; Department of Neurosurgery, Kyoto Prefectural University of Medicine, Kyoto, Japan., Tatsuzawa K; Department of Neurosurgery, Kyoto Prefectural University of Medicine, Kyoto, Japan., Hashimoto N; Department of Neurosurgery, Kyoto Prefectural University of Medicine, Kyoto, Japan. |
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| Jazyk: | angličtina |
| Zdroj: | Surgical neurology international [Surg Neurol Int] 2021 Jun 14; Vol. 12, pp. 283. Date of Electronic Publication: 2021 Jun 14 (Print Publication: 2021). |
| DOI: | 10.25259/SNI_332_2021 |
| Abstrakt: | Background: Here, we report a patient who presented with both symptomatic acromegaly and symptomatic Chiari I malformation (CM1) with a C2-T5 syrinx. Case Description: A 63-year-old female presented with bilateral arm dysesthesias and back pain. For approximately the past 30 years, she had chronic signs of acromegaly (i.e. an enlarged forehead, jaw, and nose, and enlarged hands and feet). When the cervical magnetic resonance showed a CM1 (tonsillar herniation) with C2-T5 syringomyelia, she underwent foramen magnum decompression and C1 posterior arch resection. Postoperatively, she was asymptomatic. The added finding of a growth hormone (GH)-producing pituitary lesion was treated medically with endocrine therapy, as she had incidentally required surgery/chemotherapy for a newly diagnosed colon cancer. Conclusion: Symptomatic CM1, syrinx, and acromegaly may occur together. Appropriately treatment may include a suboccipital decompression, and C1 arch resection surgery, followed by either surgical or medical treatment for the GH-producing pituitary adenoma. Competing Interests: There are no conflicts of interest. (Copyright: © 2021 Surgical Neurology International.) |
| Databáze: | MEDLINE |
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