Do Lifestyle Interventions in Pregnant Women with Overweight or Obesity Have an Effect on Neonatal Adiposity? A Systematic Review with Meta-Analysis.

Autor: Baroni NF; Graduate Program in Public Health, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14049-900, SP, Brazil., Baldoni NR; Graduate Program in Health Sciences, Federal University of São João del-Rei, São João del-Rei 36307-352, MG, Brazil.; Undergraduate Course in Nutrition, Itaúna University, Itaúna 35680-142, MG, Brazil., Alves GCS; Graduate Program in Health Sciences, Federal University of São João del-Rei, São João del-Rei 36307-352, MG, Brazil.; Undergraduate Course in Nursing, Itaúna University, Itaúna 35680-142, MG, Brazil., Crivellenti LC; Graduate Program in Public Health, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14049-900, SP, Brazil., Braga GC; Graduate Program in Public Health, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14049-900, SP, Brazil., Sartorelli DS; Department of Social Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14049-900, SP, Brazil.
Jazyk: angličtina
Zdroj: Nutrients [Nutrients] 2021 Jun 01; Vol. 13 (6). Date of Electronic Publication: 2021 Jun 01.
DOI: 10.3390/nu13061903
Abstrakt: Excessive body fat at birth is a risk factor for the development of childhood obesity. The aim of the present systematic review with meta-analysis was to evaluate the effect of lifestyle interventions in pregnant women with overweight or obesity on neonatal adiposity. The PubMed, Embase, Web of Science, Scopus, and LILACS databases were used as information sources. Original articles from randomized clinical trials of lifestyle intervention studies on pregnant women with excessive body weight and the effect on neonatal adiposity were considered eligible. The risk of bias was assessed using Cochrane criteria. The meta-analysis was calculated using the inverse variance for continuous data expressed as mean difference (MD), using the random effect model with a 95% confidence interval (CI). The outcomes were submitted to the GRADE evaluation. Of 2877 studies, four were included in the qualitative and quantitative synthesis ( n = 1494). All studies were conducted in developed countries, with three including pregnant women with overweight or obesity, and one only pregnant women with obesity. The interventions had no effect on neonatal adiposity [Heterogeneity = 56%, MD = -0.21, CI = (-0.92, 0.50)] with low confidence in the evidence, according to GRADE. Studies are needed in low- and medium-developed countries with different ethnic-racial populations. PROSPERO (CRD42020152489).
Databáze: MEDLINE