Paper-Based Optode Devices (PODs) for Selective Quantification of Potassium in Biological Fluids.

Autor: Lookadoo DB; Jana Care, Inc., Boston, Massachusetts 02215, United States., Schonhorn JE; Jana Care, Inc., Boston, Massachusetts 02215, United States., Harpaldas H; Jana Care, Inc., Boston, Massachusetts 02215, United States., Uherek CM; Jana Care, Inc., Boston, Massachusetts 02215, United States., Schatz P; Precision Medicine & Biosamples, R&D, AstraZeneca, Gothenburg, Sweden., Lindgren A; Precision Medicine & Biosamples, R&D, AstraZeneca, Gothenburg, Sweden., Depa M; Jana Care, Inc., Boston, Massachusetts 02215, United States., Kumar AA; Jana Care, Inc., Boston, Massachusetts 02215, United States.
Jazyk: angličtina
Zdroj: Analytical chemistry [Anal Chem] 2021 Jul 13; Vol. 93 (27), pp. 9383-9389. Date of Electronic Publication: 2021 Jun 30.
DOI: 10.1021/acs.analchem.1c00794
Abstrakt: This paper describes the design, fabrication, and feasibility of paper-based optode devices (PODs) for sensing potassium selectively in biological fluids. PODs operate in exhaustive mode and integrate with a handheld, smartphone-connected optical reader. This integrated measuring system provides significant advantages over traditional optode membranes and other paper-based designs, by obtaining a linear optical response to potassium concentration via a simple, stackable design and by harnessing a smartphone to provide an easy-to-use interface, thus enabling remote monitoring of diseases.
Databáze: MEDLINE