Flight and Climbing Assay for Assessing Motor Functions in Drosophila .

Autor: Manjila SB; National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, India., Hasan G; National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, India.
Jazyk: angličtina
Zdroj: Bio-protocol [Bio Protoc] 2018 Mar 05; Vol. 8 (5), pp. e2742. Date of Electronic Publication: 2018 Mar 05 (Print Publication: 2018).
DOI: 10.21769/BioProtoc.2742
Abstrakt: Motor control requires the central nervous system to integrate different sensory inputs and convey this information to the relevant central pattern generator for execution of motor function through motor neurons and muscles. Proper motor control is essential for any mobile organism to survive and interact with the external environment. For flying insects, motor control is required for flying, walking, feeding and mating apart from other more advanced behaviours such as grooming and aggression. Any perturbation to the sensory input or malfunctioning of neural connections to the motor output can result in motor defects. Here, we describe simple protocols for assessing flight and climbing ability of fruit flies, which can be used as two general tests to assess their motor function.
(Copyright © 2018 The Authors; exclusive licensee Bio-protocol LLC.)
Databáze: MEDLINE