Why do We Use the Concepts of Adult Anesthesia Pharmacology in Developing Brains? Will It Have an Impact on Outcomes? Challenges in Neuromonitoring and Pharmacology in Pediatric Anesthesia.

Autor: Sepúlveda PO; Hospital Base San José de Osorno, Service Anesthesiology and Pain, Faculty of Medicine, University Austral, Los Lagos 529000, Chile., Epulef V; Department of Surgery, Traumatology and Anesthesiology, Medicine Faculty, Universidad de La Frontera, Temuco 4780000, Chile.; Hospital Hernán Henriquez Aravena, Temuco 4780000, Chile., Campos G; Hospital Pediatrico Niño Jesús, Service of Anesthesiology, Córdoba 5500, Argentina.
Jazyk: angličtina
Zdroj: Journal of clinical medicine [J Clin Med] 2021 May 18; Vol. 10 (10). Date of Electronic Publication: 2021 May 18.
DOI: 10.3390/jcm10102175
Abstrakt: Background: Pediatric sedation and anesthesia techniques have plenty of difficulties and challenges. Data on the pharmacologic, electroencephalographic, and neurologic response to anesthesia at different brain development times are only partially known. New data in neuroscience, pharmacology, and intraoperative neuromonitoring will impact changing concepts and clinical practice. In this article, we develop a conversation to guide the debate and search for a view more attuned to the updated knowledge in neurodevelopment, electroencephalography, and clinical pharmacology for the anesthesiologic practice in the pediatric population.
Databáze: MEDLINE
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