Identification of biosynthetic intermediates for the mating hormone α2 of the plant pathogen Phytophthora.

Autor:	Ariyoshi S; Graduate School of Bioagricultural Sciences, Nagoya University, Tokai National Higher Education and Research System, Chikusa-ku, Nagoya, Japan., Imazu Y; Graduate School of Bioagricultural Sciences, Nagoya University, Tokai National Higher Education and Research System, Chikusa-ku, Nagoya, Japan., Ohguri R; Graduate School of Agriculture, Tokyo Agricultural University, Setagaya-ku, Tokyo, Japan., Katsuta R; Department of Chemistry for Life Sciences and Agriculture, Faculty of Life Sciences, Tokyo Agricultural University, Setagaya-ku, Tokyo, Japan., Yajima A; Department of Chemistry for Life Sciences and Agriculture, Faculty of Life Sciences, Tokyo Agricultural University, Setagaya-ku, Tokyo, Japan., Shibata T; Graduate School of Bioagricultural Sciences, Nagoya University, Tokai National Higher Education and Research System, Chikusa-ku, Nagoya, Japan., Ojika M; Graduate School of Bioagricultural Sciences, Nagoya University, Tokai National Higher Education and Research System, Chikusa-ku, Nagoya, Japan.
Jazyk:	angličtina
Zdroj:	Bioscience, biotechnology, and biochemistry [Biosci Biotechnol Biochem] 2021 Jul 23; Vol. 85 (8), pp. 1802-1808.
DOI:	10.1093/bbb/zbab098
Abstrakt:	The heterothallic group of the plant pathogen Phytophthora can sexually reproduce between the cross-compatible mating types A1 and A2. The mating hormone α2, produced by A2 mating type and utilized to promote the sexual reproduction of the partner A1 type, is known to be biosynthesized from phytol. In this study, we identified 2 biosynthetic intermediates, 11- and 16-hydroxyphytols (1 and 2), for α2 by administering the synthetic intermediates to an A2-type strain to produce α2 and by administering phytol to A2 strains to detect the intermediates in the mycelia. The results suggest that α2 is biosynthesized by possibly 2 cytochrome P450 oxygenases via 2 hydroxyphytol intermediates (1 and 2) in A2 hyphae and secreted outside. (© The Author(s) 2021. Published by Oxford University Press on behalf of Japan Society for Bioscience, Biotechnology, and Agrochemistry.)
Databáze:	MEDLINE
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