Inflammation in Viral Vector-Mediated Ocular Gene Therapy: A Review and Report From a Workshop Hosted by the Foundation Fighting Blindness, 9/2020.
| Autor: | Chan YK; Harvard Medical School, Boston, MA, USA., Dick AD; UCL Institute of Ophthalmology, London, UK.; University of Bristol, Bristol, UK., Hall SM; Hubble Therapeutics, Boston, MA, USA., Langmann T; University Hospital, Cologne, Germany., Scribner CL; Oakland, CA, USA., Mansfield BC; Foundation Fighting Blindness, Columbia, MD, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Translational vision science & technology [Transl Vis Sci Technol] 2021 Apr 01; Vol. 10 (4), pp. 3. |
| DOI: | 10.1167/tvst.10.4.3 |
| Abstrakt: | Translational Relevance: Subclinical or clinical inflammation often arises during ocular gene therapy with viral vectors. Understanding the biological bases and impacts on efficacy are important for clinical management and the improvement of future therapies. |
| Databáze: | MEDLINE |
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