SARS-CoV-2 RNA: Exclusive friends and common foes.

Autor: LeBlanc EV; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON K7L 3N6, Canada., Colpitts CC; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON K7L 3N6, Canada. Electronic address: che.colpitts@queensu.ca.
Jazyk: angličtina
Zdroj: Cell [Cell] 2021 Apr 29; Vol. 184 (9), pp. 2276-2278.
DOI: 10.1016/j.cell.2021.04.009
Abstrakt: Infection with SARS-CoV-2 sets off a molecular arms race between virus replication and host cell defense. In this issue of Cell, Flynn, Belk, et al. integrate an advanced large-scale RNA-centered approach with custom CRISPR screens to functionally characterize the interactome of the SARS-CoV-2 RNA genome during infection.
(Copyright © 2021 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE