Educational attainment does not influence brain aging.

Autor:	Nyberg L; Department of Radiation Sciences, Radiology, Umeå University, 901 87 Umeå, Sweden; lars.nyberg@umu.se a.m.fjell@psykologi.uio.no.; Department of Integrative Medical Biology, Umeå University, 901 87 Umeå, Sweden.; Umeå Center for Functional Brain Imaging, Umeå University, 901 87 Umeå, Sweden.; Center for Lifespan Changes in Brain and Cognition, University of Oslo, 0317 Oslo, Norway., Magnussen F; Center for Lifespan Changes in Brain and Cognition, University of Oslo, 0317 Oslo, Norway., Lundquist A; Umeå Center for Functional Brain Imaging, Umeå University, 901 87 Umeå, Sweden., Baaré W; Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital, Amager and Hvidovre, 2650 Hvidovre, Denmark., Bartrés-Faz D; Department of Medicine, Faculty of Medicine and Health Sciences and Neurosciences Institute, University of Barcelona, 08014 Barcelona, Spain., Bertram L; Center for Lifespan Changes in Brain and Cognition, University of Oslo, 0317 Oslo, Norway.; Lübeck Interdisciplinary Platform for Genome Analytics, University of Lübeck, 23538 Lübeck, Germany., Boraxbekk CJ; Department of Radiation Sciences, Radiology, Umeå University, 901 87 Umeå, Sweden.; Umeå Center for Functional Brain Imaging, Umeå University, 901 87 Umeå, Sweden.; Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital, Amager and Hvidovre, 2650 Hvidovre, Denmark.; Institute of Sports Medicine Copenhagen, Copenhagen University Hospital, Bispebjerg, 2400 Copenhagen, Denmark., Brandmaier AM; Center for Lifespan Psychology, Max Planck Institute for Human Development, D-14195 Berlin, Germany.; Max Planck University College London Centre for Computational Psychiatry and Ageing Research, D-14195 Berlin, Germany, and London WC1B 5EH, United Kingdom., Drevon CA; Vitas AS, Research Park, 0349 Oslo, Norway.; Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, Medicine/University of Oslo, 0317 Oslo, Norway., Ebmeier K; Warneford Hospital, University of Oxford, Oxford OX3 7JX, United Kingdom., Ghisletta P; Faculté de Psychologie et des Sciences de l'Education, Université de Genève, 1205 Geneva, Switzerland., Henson RN; Medical Research Council Cognition and Brain Sciences Unit, Department of Psychiatry, University of Cambridge, Cambridge CB2 7EF, United Kingdom., Junqué C; Department of Medicine, Faculty of Medicine and Health Sciences and Neurosciences Institute, University of Barcelona, 08014 Barcelona, Spain., Kievit R; Medical Research Council Cognition and Brain Sciences Unit, Department of Psychiatry, University of Cambridge, Cambridge CB2 7EF, United Kingdom.; Cognitive Neuroscience Department, Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, 6500 GL Nijmegen, The Netherlands., Kleemeyer M; Center for Lifespan Psychology, Max Planck Institute for Human Development, D-14195 Berlin, Germany., Knights E; Medical Research Council Cognition and Brain Sciences Unit, Department of Psychiatry, University of Cambridge, Cambridge CB2 7EF, United Kingdom., Kühn S; Center for Lifespan Psychology, Max Planck Institute for Human Development, D-14195 Berlin, Germany.; Department of Psychiatry and Psychotherapy, University Clinic Hamburg-Eppendorf, 20251 Hamburg, Germany., Lindenberger U; Center for Lifespan Psychology, Max Planck Institute for Human Development, D-14195 Berlin, Germany.; Max Planck University College London Centre for Computational Psychiatry and Ageing Research, D-14195 Berlin, Germany, and London WC1B 5EH, United Kingdom., Penninx BWJH; Department of Psychiatry, Amsterdam University Medical Center, Vrije Universiteit, 1081 HJ Amsterdam, The Netherlands., Pudas S; Department of Integrative Medical Biology, Umeå University, 901 87 Umeå, Sweden.; Umeå Center for Functional Brain Imaging, Umeå University, 901 87 Umeå, Sweden., Sørensen Ø; Center for Lifespan Changes in Brain and Cognition, University of Oslo, 0317 Oslo, Norway., Vaqué-Alcázar L; Department of Medicine, Faculty of Medicine and Health Sciences and Neurosciences Institute, University of Barcelona, 08014 Barcelona, Spain., Walhovd KB; Center for Lifespan Changes in Brain and Cognition, University of Oslo, 0317 Oslo, Norway.; Department of Radiology and Nuclear Medicine, Oslo University Hospital, 0372 Oslo, Norway., Fjell AM; Center for Lifespan Changes in Brain and Cognition, University of Oslo, 0317 Oslo, Norway; lars.nyberg@umu.se a.m.fjell@psykologi.uio.no.; Department of Radiology and Nuclear Medicine, Oslo University Hospital, 0372 Oslo, Norway.
Jazyk:	angličtina
Zdroj:	Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 May 04; Vol. 118 (18).
DOI:	10.1073/pnas.2101644118
Abstrakt:	Education has been related to various advantageous lifetime outcomes. Here, using longitudinal structural MRI data (4,422 observations), we tested the influential hypothesis that higher education translates into slower rates of brain aging. Cross-sectionally, education was modestly associated with regional cortical volume. However, despite marked mean atrophy in the cortex and hippocampus, education did not influence rates of change. The results were replicated across two independent samples. Our findings challenge the view that higher education slows brain aging. Competing Interests: The authors declare no competing interest. (Copyright © 2021 the Author(s). Published by PNAS.)
Databáze:	MEDLINE
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