Insights from a Pan India Sero-Epidemiological survey (Phenome-India Cohort) for SARS-CoV2.

Autor:	Naushin S; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Sardana V; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Ujjainiya R; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Bhatheja N; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India., Kutum R; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Bhaskar AK; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Pradhan S; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India., Prakash S; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India., Khan R; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Advanced Materials and Processes Research Institute, Bhopal, India., Rawat BS; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Building Research Institute, Roorkee, India., Tallapaka KB; CSIR-Centre for Cellular Molecular Biology, Hyderabad, India., Anumalla M; CSIR-Centre for Cellular Molecular Biology, Hyderabad, India., Chandak GR; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Centre for Cellular Molecular Biology, Hyderabad, India., Lahiri A; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Drug Research Institute, Lucknow, India., Kar S; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Drug Research Institute, Lucknow, India., Mulay SR; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Drug Research Institute, Lucknow, India., Mugale MN; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Drug Research Institute, Lucknow, India., Srivastava M; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Drug Research Institute, Lucknow, India., Khan S; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Drug Research Institute, Lucknow, India., Srivastava A; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Drug Research Institute, Lucknow, India., Tomar B; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Drug Research Institute, Lucknow, India., Veerapandian M; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Electrochemical Research Institute, Karaikudi, India., Venkatachalam G; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Electrochemical Research Institute, Karaikudi, India., Vijayakumar SR; CSIR-Central Electrochemical Research Institute, Karaikudi, India., Agarwal A; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Electronics Engineering Research Institute, Pilani, India., Gupta D; CSIR-Central Electronics Engineering Research Institute, Pilani, India., Halami PM; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Food Technological Research Institute, Mysore, India., Peddha MS; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Food Technological Research Institute, Mysore, India., Sundaram GM; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Food Technological Research Institute, Mysore, India., Veeranna RP; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Food Technological Research Institute, Mysore, India., Pal A; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Institute of Medicinal Aromatic Plants, Lucknow, India., Agarwal VK; CSIR-Central Institute of Medicinal Aromatic Plants, Lucknow, India., Maurya AK; CSIR-Central Institute of Medicinal Aromatic Plants, Lucknow, India., Singh RK; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Institute of Mining and Fuel Research, Dhanbad, India., Raman AK; CSIR-Central Institute of Mining and Fuel Research, Dhanbad, India., Anandasadagopan SK; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Leather Research Institute, Chennai, India., Karuppanan P; CSIR-Central Leather Research Institute, Chennai, India., Venkatesan S; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Leather Research Institute, Chennai, India., Sardana HK; CSIR-Central Scientific Instruments Organization, Chandigarh, India., Kothari A; CSIR-Central Scientific Instruments Organization, Chandigarh, India., Jain R; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Scientific Instruments Organization, Chandigarh, India., Thakur A; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Scientific Instruments Organization, Chandigarh, India., Parihar DS; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Scientific Instruments Organization, Chandigarh, India., Saifi A; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Scientific Instruments Organization, Chandigarh, India., Kaur J; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Scientific Instruments Organization, Chandigarh, India., Kumar V; CSIR-Central Scientific Instruments Organization, Chandigarh, India., Mishra A; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Central Salt Marine Chemicals Research Institute, Bhavnagar, India., Gogeri I; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR Fourth Paradigm Institute, Bengaluru, India., Rayasam G; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR- Headquarters, Rafi Marg, New Delhi, India., Singh P; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Chakraborty R; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Chaturvedi G; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Karunakar P; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Yadav R; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Singhmar S; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India., Singh D; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Sarkar S; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Bhattacharya P; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Acharya S; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Singh V; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Verma S; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Soni D; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Seth S; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Vashisht S; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Thakran S; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Fatima F; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Singh AP; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Sharma A; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Sharma B; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Subramanian M; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India., Padwad YS; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Institute of Himalayan Bioresource Technology, Palampur, India., Hallan V; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Institute of Himalayan Bioresource Technology, Palampur, India., Patial V; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Institute of Himalayan Bioresource Technology, Palampur, India., Singh D; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Institute of Himalayan Bioresource Technology, Palampur, India., Tripude NV; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Institute of Himalayan Bioresource Technology, Palampur, India., Chakrabarti P; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Indian Institute of Chemical Biology, Kolkata, India., Maity SK; CSIR-Indian Institute of Chemical Biology, Kolkata, India., Ganguly D; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Indian Institute of Chemical Biology, Kolkata, India., Sarkar J; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Indian Institute of Chemical Biology, Kolkata, India., Ramakrishna S; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Indian Institute of Chemical Technology, Hyderabad, India., Kumar BN; CSIR-Indian Institute of Chemical Technology, Hyderabad, India., Kumar KA; CSIR-Indian Institute of Chemical Technology, Hyderabad, India., Gandhi SG; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Indian Institute of Integrative Medicine, Jammu, India., Jamwal PS; CSIR-Indian Institute of Integrative Medicine, Jammu, India., Chouhan R; CSIR-Indian Institute of Integrative Medicine, Jammu, India., Jamwal VL; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Indian Institute of Integrative Medicine, Jammu, India., Kapoor N; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Indian Institute of Integrative Medicine, Jammu, India., Ghosh D; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Indian Institute of Petroleum, Dehradun, India., Thakkar G; CSIR-Indian Institute of Petroleum, Dehradun, India., Subudhi U; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Institute of Minerals and Materials Technology, Bhubaneswar, India., Sen P; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Institute of Microbial Technology, Chandigarh, India., Chaudhury SR; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Institute of Microbial Technology, Chandigarh, India., Kumar R; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Institute of Microbial Technology, Chandigarh, India., Gupta P; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Institute of Microbial Technology, Chandigarh, India., Tuli A; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Institute of Microbial Technology, Chandigarh, India., Sharma D; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-Institute of Microbial Technology, Chandigarh, India., Ringe RP; CSIR-Institute of Microbial Technology, Chandigarh, India., D A; CSIR- National Aerospace Laboratories, Bengaluru, India., Kulkarni M; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-National Chemical Laboratory, Pune, India., Shanmugam D; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-National Chemical Laboratory, Pune, India., Dharne MS; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-National Chemical Laboratory, Pune, India., Dastager SG; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-National Chemical Laboratory, Pune, India., Joshi R; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-National Chemical Laboratory, Pune, India., Patil AP; CSIR-National Chemical Laboratory, Pune, India., Mahajan SN; CSIR-National Chemical Laboratory, Pune, India., Khan AH; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-National Chemical Laboratory, Pune, India., Wagh V; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-National Chemical Laboratory, Pune, India., Yadav RK; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-National Chemical Laboratory, Pune, India., Khilari A; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-National Chemical Laboratory, Pune, India., Bhadange M; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-National Chemical Laboratory, Pune, India., Chaurasiya AH; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-National Chemical Laboratory, Pune, India., Kulsange SE; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-National Chemical Laboratory, Pune, India., Khairnar K; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-National Environmental Engineering Research Institute, Nagpur, India., Paranjape S; CSIR-National Environmental Engineering Research Institute, Nagpur, India., Kalita J; CSIR-North - East Institute of Science and Technology, Jorhat, India., Sastry NG; CSIR-North - East Institute of Science and Technology, Jorhat, India., Phukan T; CSIR-North - East Institute of Science and Technology, Jorhat, India., Manna P; CSIR-North - East Institute of Science and Technology, Jorhat, India., Romi W; CSIR-North - East Institute of Science and Technology, Jorhat, India., Bharali P; CSIR-North - East Institute of Science and Technology, Jorhat, India., Ozah D; CSIR-North - East Institute of Science and Technology, Jorhat, India., Sahu RK; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-North - East Institute of Science and Technology, Jorhat, India., Babu EV; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-National Geophysical Research Institute, Hyderabad, India., Sukumaran R; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram, India., Nair AR; CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram, India., Valappil PK; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram, India., Puthiyamadam A; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram, India., Velayudhanpillai A; CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram, India., Chodankar K; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-National Institute of Oceanography, Goa, India., Damare S; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-National Institute of Oceanography, Goa, India., Madhavi Y; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-National Institute of Science, Technology and Development Studies, New Delhi, India., Aggarwal VV; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-National Physical Laboratory, New Delhi, India., Dahiya S; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; CSIR-National Physical Laboratory, New Delhi, India., Agrawal A; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Dash D; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Sengupta S; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.
Jazyk:	angličtina
Zdroj:	ELife [Elife] 2021 Apr 20; Vol. 10. Date of Electronic Publication: 2021 Apr 20.
DOI:	10.7554/eLife.66537
Abstrakt:	To understand the spread of SARS-CoV2, in August and September 2020, the Council of Scientific and Industrial Research (India) conducted a serosurvey across its constituent laboratories and centers across India. Of 10,427 volunteers, 1058 (10.14%) tested positive for SARS-CoV2 anti-nucleocapsid (anti-NC) antibodies, 95% of which had surrogate neutralization activity. Three-fourth of these recalled no symptoms. Repeat serology tests at 3 (n = 607) and 6 (n = 175) months showed stable anti-NC antibodies but declining neutralization activity. Local seropositivity was higher in densely populated cities and was inversely correlated with a 30-day change in regional test positivity rates (TPRs). Regional seropositivity above 10% was associated with declining TPR. Personal factors associated with higher odds of seropositivity were high-exposure work (odds ratio, 95% confidence interval, p value: 2.23, 1.92-2.59, <0.0001), use of public transport (1.79, 1.43-2.24, <0.0001), not smoking (1.52, 1.16-1.99, 0.0257), non-vegetarian diet (1.67, 1.41-1.99, <0.0001), and B blood group (1.36, 1.15-1.61, 0.001). Competing Interests: SN, VS, RU, NB, RK, AB, SP, SP, RK, BR, KT, MA, GC, AL, SK, SM, MM, MS, SK, AS, BT, MV, GV, SV, AA, DG, PH, MP, GS, RV, AP, VA, AM, RS, AR, SA, PK, SV, HS, AK, RJ, AT, DP, AS, JK, VK, AM, IG, GR, PS, RC, GC, PK, RY, SS, DS, SS, PB, SA, VS, SV, DS, SS, SV, ST, FF, AS, AS, BS, MS, YP, VH, VP, DS, NT, PC, SM, DG, JS, SR, BK, KK, SG, PJ, RC, VJ, NK, DG, GT, US, PS, SC, RK, PG, AT, DS, RR, AD, MK, DS, MD, SD, RJ, AP, SM, AK, VW, RY, AK, MB, AC, SK, KK, SP, JK, NS, TP, PM, WR, PB, DO, RS, EB, RS, AN, PV, AP, AV, KC, SD, YM, VA, SD, AA, DD, SS No competing interests declared (© 2021, Naushin et al.)
Databáze:	MEDLINE
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