The Infant Microbiome and Its Impact on Development of Food Allergy.
| Autor: | Jungles KN; Department of Pediatrics, University of Michigan C.S. Mott Children's Hospital, 1540 E Hospital Dr #4204, Ann Arbor, MI 48109, USA; Department of Internal Medicine, Allergy and Immunology Division, Rush University Medical Center, 1725 West Harrison Street, Suite 117, Chicago, IL 60612, USA., Jungles KM; Department of Pharmacology, University of Michigan, 1150 W Medical Center Dr, Ann Arbor, MI 48109, USA., Greenfield L; Department of Internal Medicine, Allergy and Immunology Division, Rush University Medical Center, 1725 West Harrison Street, Suite 117, Chicago, IL 60612, USA; Rush Medical College, 600 S Paulina St Suite 524, Chicago, IL 60612, USA., Mahdavinia M; Department of Internal Medicine, Allergy and Immunology Division, Rush University Medical Center, 1725 West Harrison Street, Suite 117, Chicago, IL 60612, USA. Electronic address: Mahboobeh_mahdavinia@rush.edu. |
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| Jazyk: | angličtina |
| Zdroj: | Immunology and allergy clinics of North America [Immunol Allergy Clin North Am] 2021 May; Vol. 41 (2), pp. 285-299. Date of Electronic Publication: 2021 Mar 24. |
| DOI: | 10.1016/j.iac.2021.01.004 |
| Abstrakt: | The prevalence of food allergy (FA) has been increasing over the past few decades; recent statistics suggest that FA has an impact on up to 10% of the population and 8% of children. Although the pathogenesis of FA is unclear, studies suggest gut microbiome plays a role in the development of FA. The gut microbiome is influenced by infant feeding method, infant diet, and maternal diet during lactation. Breastfeeding, Mediterranean diet, and probiotics are associated with commensal gut microbiota that protect against FA. This area of research is essential to discovering potential preventive methods or therapeutic targets against FA. Competing Interests: Disclosure None of the authors have any conflict of interest related to this research. M. Mahdavinia is supported by NIH and Brinson Foundation for research in FA. (Copyright © 2021 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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