Serological evidence of West Nile virus infection in human populations and domestic birds in the Northwest of Morocco.

Autor: Assaid N; Institut Pasteur du Maroc, Service de Parasitologie et des Maladies Vectorielles, Place Louis Pasteur, Casablanca 20360, Morocco; Molecular Genetics and Immunophysiopathology Research Team, Health and Environment Laboratory, Aïn Chock Faculty of Sciences, University of Hassan II Casablanca (UH2C), Casablanca, Morocco. Electronic address: najlaa.essaid@gmail.com., Arich S; Institut Pasteur du Maroc, Service de Parasitologie et des Maladies Vectorielles, Place Louis Pasteur, Casablanca 20360, Morocco. Electronic address: arichsoukaina@gmail.com., Ezzikouri S; Virology Unit, Viral Hepatitis Laboratory, Institut Pasteur du Maroc 1, Place Louis Pasteur, 20360 Casablanca, Morocco. Electronic address: sayeh.ezzikouri@pasteur.ma., Benjelloun S; Virology Unit, Viral Hepatitis Laboratory, Institut Pasteur du Maroc 1, Place Louis Pasteur, 20360 Casablanca, Morocco. Electronic address: soumaya.benjelloun@pasteur.ma., Dia M; Virology Department, Institut Pasteur de Dakar, 36 Avenue Pasteur, Dakar, Senegal. Electronic address: moussa.dia@pasteur.sn., Faye O; Virology Department, Institut Pasteur de Dakar, 36 Avenue Pasteur, Dakar, Senegal. Electronic address: oumar.faye@pasteur.msn., Akarid K; Molecular Genetics and Immunophysiopathology Research Team, Health and Environment Laboratory, Aïn Chock Faculty of Sciences, University of Hassan II Casablanca (UH2C), Casablanca, Morocco. Electronic address: kakarid@yahoo.fr., Beck C; UMR1161 Virologie, INRAE, ANSES, Ecole Nationale Vétérinaire d'Alfort, Université Paris-Est, Maisons-Alfort, France. Electronic address: cecile.beck@anses.fr., Lecollinet S; UMR1161 Virologie, INRAE, ANSES, Ecole Nationale Vétérinaire d'Alfort, Université Paris-Est, Maisons-Alfort, France. Electronic address: sylvie.lecollinet@anses.fr., Failloux AB; Department of Virology, Institut Pasteur, Arboviruses and Insect Vectors Unit, Paris, France. Electronic address: anna-bella.failloux@pasteur.fr., Sarih M; Institut Pasteur du Maroc, Service de Parasitologie et des Maladies Vectorielles, Place Louis Pasteur, Casablanca 20360, Morocco. Electronic address: mhammed.sarih@pasteur.ma.
Jazyk: angličtina
Zdroj: Comparative immunology, microbiology and infectious diseases [Comp Immunol Microbiol Infect Dis] 2021 Jun; Vol. 76, pp. 101646. Date of Electronic Publication: 2021 Apr 05.
DOI: 10.1016/j.cimid.2021.101646
Abstrakt: West Nile virus (WNV) was recently detected in Culex pipiens mosquitoes in Morocco. The aim of this study was to evaluate the seroprevalence of WNV in humans and in domestic birds in two regions of Morocco by the detection of IgG antibodies. Blood samples were obtained from 91 human patients and 92 domestic birds from September to December 2019. All study samples were tested using competitive enzyme-linked immunosorbent assay (cELISA) and WNV neutralization tests (VNT) were performed on positive sera. Of all samples, 4 (4.39 %) humans and 4 (4.34 %) birds were found to be seropositive for flaviviruses by the cELISA test. The VNT revealed that three of the four human samples detected positive by cELISA contained neutralizing antibodies against WNV. Two bird samples were confirmed positive by VNT. These results show a significant seroprevalence of anti-WNV antibodies and therefore suggest the active circulation and exposure of human and bird populations in the northwest of Morocco.
(Copyright © 2021 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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