Current co-morbidities burden in patients living with HIV in low- and middle-income countries.
| Autor: | Ponatshego PL; Research Physician and Principal Investigator, Botswana Harvard HIV/AIDS Partnership., Youssouf NF; Program Manager, Botswana Harvard HIV/AIDS Partnership., Mosepele M; Associate Professor, Infectious Diseases; Head of Department, Internal Medicine, University of Botswana.; Principal Investigator, Botswana Harvard HIV/AIDS Partnership. |
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| Jazyk: | angličtina |
| Zdroj: | Current opinion in HIV and AIDS [Curr Opin HIV AIDS] 2021 May 01; Vol. 16 (3), pp. 163-167. |
| DOI: | 10.1097/COH.0000000000000676 |
| Abstrakt: | Purpose of Review: The present review aims to decipher common co-morbidities faced by people living with HIV in low- to middle-income countries, and in particular the sub-Saharan region, which hosts the majority of the HIV burden worldwide. Recent Findings: Well-controlled chronic HIV disease is strongly associated with an increased risk of developing cardiovascular disease. This is partly due to the natural aging process, however recent studies show that using antiretroviral therapy as well as the HIV disease itself may be predisposing factors to the development of cardiovascular diseases, creating a new burden for healthcare facilities in the region. Furthermore, newly completed studies assessing inflammation marker albuminuria and age-related syndrome frailty have been found in a higher prevalence than in non-HIV people, with increased morbidity and mortality. Summary: As antiretroviral medication continues to be well supplied in the region and well tolerated by patients living with HIV, this group is now reckoning with cardiovascular ailments faced by all ageing population therefore there is a need for cardiovascular care systems to be better integrated within the existing, well-performing HIV care cascade to address this burden. (Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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