| Autor: |
Manteghi F; Research Laboratory of Inorganic Chemistry and Environment, Department of Chemistry, Iran University of Science and Technology, Narmak, Tehran 1684613114, Iran., Zakeri F; Research Laboratory of Inorganic Chemistry and Environment, Department of Chemistry, Iran University of Science and Technology, Narmak, Tehran 1684613114, Iran., Guy OJ; Department of Chemistry, College of Science, Swansea University, Singleton Park, Swansea SA2 8PP, UK., Tehrani Z; Centre for NanoHealth, College of Engineering, Institute of Life Science-2, Swansea University, Singleton Park, Swansea SA2 8PP, UK. |
| Jazyk: |
angličtina |
| Zdroj: |
Nanomaterials (Basel, Switzerland) [Nanomaterials (Basel)] 2021 Mar 26; Vol. 11 (4). Date of Electronic Publication: 2021 Mar 26. |
| DOI: |
10.3390/nano11040845 |
| Abstrakt: |
A chromium-containing metal-organic framework (MOF), MIL-101 (Chromium(III) benzene-1,4-dicarboxylate), was used to catalyze the one pot, three component synthesis of some 2,4,5-trisubstituted imidazoles under solvent-free conditions. The advantages of using this heterogeneous catalyst include short reaction time, high yields, easy and quick isolation of catalyst and products, low amount of catalyst needed, and that the addition of solvent, salt, and additives are not needed. This catalyst is highly efficient and can be recovered at least 5 times with a slight loss of efficiency. The structure of the metal-organic frameworks (MOF) was confirmed by X-ray diffraction (XRD) and field emission scanning electron microscopy (FESEM). Fourier transform infrared spectroscopy (FTIR) and proton nuclear magnetic resonance (HNMR) were performed to confirm some of the synthesized products. Experimental data indicated that the optimum amount of catalyst was 5 mg for benzil (1 mmol), 4-chlorobenzaldehyde (1 mmol), and ammonium acetate (2.5 mmol), and the synthetic route to the various imidazoles is performed in 10 min by 95% yield, an acceptable result rivalling those of other catalysts. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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