Demographic History, Adaptation, and NRAP Convergent Evolution at Amino Acid Residue 100 in the World Northernmost Cattle from Siberia.

Autor:	Buggiotti L; Royal Veterinary College, University of London, London, United Kingdom., Yurchenko AA; The Federal Research Center Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences (ICG SB RAS), Novosibirsk, Russia.; Kurchatov Genomics Center, Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Science, Novosibirsk, Russia., Yudin NS; The Federal Research Center Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences (ICG SB RAS), Novosibirsk, Russia.; Kurchatov Genomics Center, Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Science, Novosibirsk, Russia., Vander Jagt CJ; Agriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, VIC, Australia., Vorobieva NV; Department of the Diversity and Evolution of Genomes, Institute of Molecular and Cellular Biology SB RAS, Novosibirsk, Russia., Kusliy MA; Department of the Diversity and Evolution of Genomes, Institute of Molecular and Cellular Biology SB RAS, Novosibirsk, Russia., Vasiliev SK; Paleometal Archeology Department, Institute of Archaeology and Ethnography SB RAS, Novosibirsk, Russia., Rodionov AN; L.K. Ernst Federal Research Centre for Animal Husbandry, Podolsk, Russia., Boronetskaya OI; Moscow Agrarian Academy, Timiryazev Russian State Agrarian University, Moscow, Russia., Zinovieva NA; L.K. Ernst Federal Research Centre for Animal Husbandry, Podolsk, Russia., Graphodatsky AS; Department of the Diversity and Evolution of Genomes, Institute of Molecular and Cellular Biology SB RAS, Novosibirsk, Russia., Daetwyler HD; Agriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, VIC, Australia.; School of Applied Systems Biology, La Trobe University, Bundoora, VIC, Australia., Larkin DM; Royal Veterinary College, University of London, London, United Kingdom.; The Federal Research Center Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences (ICG SB RAS), Novosibirsk, Russia.; Kurchatov Genomics Center, Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Science, Novosibirsk, Russia.
Jazyk:	angličtina
Zdroj:	Molecular biology and evolution [Mol Biol Evol] 2021 Jul 29; Vol. 38 (8), pp. 3093-3110.
DOI:	10.1093/molbev/msab078
Abstrakt:	Native cattle breeds represent an important cultural heritage. They are a reservoir of genetic variation useful for properly responding to agriculture needs in the light of ongoing climate changes. Evolutionary processes that occur in response to extreme environmental conditions could also be better understood using adapted local populations. Herein, different evolutionary histories of the world northernmost native cattle breeds from Russia were investigated. They highlighted Kholmogory as a typical taurine cattle, whereas Yakut cattle separated from European taurines approximately 5,000 years ago and contain numerous ancestral and some novel genetic variants allowing their adaptation to harsh conditions of living above the Polar Circle. Scans for selection signatures pointed to several common gene pathways related to adaptation to harsh climates in both breeds. But genes affected by selection from these pathways were mostly different. A Yakut cattle breed-specific missense mutation in a highly conserved NRAP gene represents a unique example of a young amino acid residue convergent change shared with at least 16 species of hibernating/cold-adapted mammals from six distinct phylogenetic orders. This suggests a convergent evolution event along the mammalian phylogenetic tree and fast fixation in a single isolated cattle population exposed to a harsh climate. (© The Author(s) 2021. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.)
Databáze:	MEDLINE
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