Validation and performance comparison of two SARS-CoV-2 IgG/IgM rapid tests.

Autor:	Al Awaji NN; Department of Health Communication Sciences, College of Health and Rehabilitation Sciences, Princess Nourah Bint Abdulrahman University, P.O Box 84428, Riyadh 11671, Saudi Arabia., Ahmedah HT; Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Rabegh, Saudi Arabia., Alsaady IM; Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.; Special Infectuis Agent unit, King Fahad Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia., Bawaked RA; Centre of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia., Alraey MA; Infection Prevention and Control Department, King Abdullah bin Abdulaziz University Hospital, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia., Alasiri AA; Department of Pathology and Laboratory Medicine, Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabia., Alfaifi AM; Department of Pathology and Laboratory Medicine, King Abdullah Bin Abdulaziz University Hospital, Riyadh, Saudi Arabia., Alshehri HA; Department of Pathology and Clinical Laboratory, King Abdullah Bin Abdulaziz University Hospital, Riyadh, Saudi Arabia., Alserihi R; Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia., Yasin EB; Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Rabigh, Saudi Arabia.
Jazyk:	angličtina
Zdroj:	Saudi journal of biological sciences [Saudi J Biol Sci] 2021 Jun; Vol. 28 (6), pp. 3433-3437. Date of Electronic Publication: 2021 Mar 14.
DOI:	10.1016/j.sjbs.2021.03.007
Abstrakt:	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a disease called COVID-19. COVID-19 is primarily diagnosed using molecular techniques mainly real-time reverse transcriptase PCR. Reliable and accurate serologic assays for COVID-19, are an important tool for surveillance and epidemiologic studies. In this study, the IgG/IgM Rapid Test Cassette and the Prima COVID-19 IgG/IgM Rapid Test for the detection of SARS-CoV-2 antibodies in blood, serum and plasma samples collected from patients up to 48 days after symptom onset in Saudi Arabia were validated. Overall, both tests showed poor performance and cannot be utilised for COVID-19 diagnosis as a point of care test or to determine seroprevalence. Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (© 2021 The Authors.)
Databáze:	MEDLINE
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