Relative Frequency of Blood-Borne Viruses in Hemodialysis-Dependent and Kidney Transplant Recipients in Iran.

Autor:	Hatatian F; Inflammation and Inflammatory Disease Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Babakhani F; Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran., Gudarzi H; Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran., Momenifar N; Human and Animal Cell Bank, Iranian Biological Resource Center, Academic Center of Education, Culture and Research, Tehran, Iran., Norouzi M; Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.; Research Center for Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran., Shafieifar M; Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran., Kakavandi E; Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran., Sadeghi A; Iranian Tissue Bank and Research Center, Tehran University of Medical Sciences, Tehran, Iran., Sharbatdar-Alaei H; Department of Microbial Biotechnology, Faculty of Basic Sciences and Advanced Technologies in Biology, University of Science and Culture, Tehran, Iran., Farahmand M; Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran., Amiri-Roudy M; Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran., Jahantigh HR; Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran., Madihi M; Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran., Borhani K; Department of Virology, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran., Ajorloo M; Hepatitis Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.; Department of Clinical Laboratory Sciences, School of Allied Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran., Hedayat Yaghoobi M; Department of Infectious Disease, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Jazyk:	angličtina
Zdroj:	Iranian journal of public health [Iran J Public Health] 2020 Nov; Vol. 49 (11), pp. 2136-2143.
DOI:	10.18502/ijph.v49i11.4731
Abstrakt:	Background: Hemodialysis (HD) patients and kidney transplant (KT) recipients are exposed to be infected by blood-borne viruses (BBVs). Current study was conducted to evaluate the prevalence of BBVs in HD and KT patients in the whole Iranian population. Methods: From Jan 2016 to Dec 2017, 174 hemodialysis and 139 kidney transplant recipients enrolled in this survey. After blood sampling, serum samples were detected for HBV, HCV, HCMV, HIV and HTLV antibodies. Seropositive samples confirmed by Polymerase chain reaction (PCR) method. Results: Overall, 6 (3.44%) and 3 (2.15%) of hemodialysis-dependent and transplantation patients had evidence of HCV infection, whereas no patients were HIV and HBV positive, two cases (1.14%) of hemodialysis and one case (0.71%) of transplantation patients demonstrated the HTLV-1 infection. 52 (37.4%) of patients received graft were positive for HCMV antibody. In addition, our study showed a co-infection of HCMV with HCV (3 patients, 2.15%) in transplantation patients. Conclusion: Prevalence of BBVs infection was lower in comparison to the previous studies. The current strict infection control practices in Iran appear to be effective in limiting dialysis and related infections after transplantation. Because BBVs infections constantly occur especially in dialysis and after transplantation units, our data will be useful to build a new strategic plan for the elimination of BBVs infection in kidney therapycenters. Competing Interests: Conflict of interest The authors declare that there is no conflict of interest. (Copyright © 2020 Hatatian et al. Published by Tehran University of Medical Sciences.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu