Six Decades of Human Adenovirus Type 4 Infections Reviewed: Increasing Infections Among Civilians Are a Matter of Concern.

Autor:	Coleman KK; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Robie ER; Duke Global Health Institute, Duke University, Durham, North Carolina, USA.; Division of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina, USA., Abdelgadir A; Duke Global Health Institute, Duke University, Durham, North Carolina, USA.; Division of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina, USA., Kozhumam AS; Duke Global Health Institute, Duke University, Durham, North Carolina, USA., Binder RA; Duke Global Health Institute, Duke University, Durham, North Carolina, USA.; Division of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina, USA., Gray GC; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.; Duke Global Health Institute, Duke University, Durham, North Carolina, USA.; Division of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina, USA.; Global Health Research Center, Duke Kunshan University, Kunshan, China.
Jazyk:	angličtina
Zdroj:	Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2021 Aug 16; Vol. 73 (4), pp. 740-746.
DOI:	10.1093/cid/ciab146
Abstrakt:	Human adenovirus type 4 (HAdV-E4) frequently causes epidemics among military and civilian populations. We conducted a systematic review of 144 peer-reviewed articles reporting HAdV-E4 infections, published during the years 1960-2020. More than 24 500 HAdV-E4 infections, including 27 associated deaths, were documented. HAdV-E4 infections were reported from all geographic regions of the world except Central America and the Caribbean. The number of publications reporting civilian infections tripled in the last decade, with a steady increase in reported civilian infections over time. Infections commonly caused respiratory and ocular disease. North America reported the most infections, followed by Asia and Europe. The majority of deaths were reported in the United States, followed by China and Singapore. Civilians seem to increasingly suffer HAdV-E4 disease, with recent epidemics among US college students. Public health officials should consider seeking emergency use authorization for the adenovirus vaccine such that it might be available to mitigate civilian epidemics. (© The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.)
Databáze:	MEDLINE
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