Low awareness of past SARS-CoV-2 infection in healthy plasma donors.

Autor:	van den Hurk K; Department of Donor Medicine Research, Sanquin Research, Amsterdam, the Netherlands., Merz EM; Department of Donor Medicine Research, Sanquin Research, Amsterdam, the Netherlands.; Department of Sociology, Vrije Universiteit, Amsterdam, the Netherlands., Prinsze FJ; Department of Donor Medicine Research, Sanquin Research, Amsterdam, the Netherlands., Spekman MLC; Department of Donor Medicine Research, Sanquin Research, Amsterdam, the Netherlands.; Department of Sociology, Vrije Universiteit, Amsterdam, the Netherlands., Quee FA; Department of Donor Medicine Research, Sanquin Research, Amsterdam, the Netherlands., Ramondt S; Department of Donor Medicine Research, Sanquin Research, Amsterdam, the Netherlands.; Department of Communication Science, Vrije Universiteit, Amsterdam, the Netherlands., Slot E; Department of Donor Medicine Research, Sanquin Research, Amsterdam, the Netherlands.; Department of Medical Affairs, Sanquin Corporate Staff, Sanquin Research, Amsterdam, the Netherlands., Vrielink H; Unit of Transfusion Medicine, Sanquin Blood Bank, Amsterdam, the Netherlands., Huis In 't Veld EMJ; Department of Donor Medicine Research, Sanquin Research, Amsterdam, the Netherlands.; Department of Cognitive Science and Artificial Intelligence, Tilburg University, Tilburg, the Netherlands., Zaaijer HL; Department of Donor Medicine Research, Sanquin Research, Amsterdam, the Netherlands.; Department of Internal Medicine, Amsterdam Infection and Immunity Institute, Academic Medical Center, Amsterdam, the Netherlands., Hogema BM; Department of Donor Medicine Research, Sanquin Research, Amsterdam, the Netherlands.; Department of Virology, Sanquin Diagnostic Services, Amsterdam, the Netherlands.
Jazyk:	angličtina
Zdroj:	Cell reports. Medicine [Cell Rep Med] 2021 Mar 16; Vol. 2 (3), pp. 100222. Date of Electronic Publication: 2021 Mar 01.
DOI:	10.1016/j.xcrm.2021.100222
Abstrakt:	Awareness of infection with SARS-CoV-2 is crucial for the effectiveness of COVID-19 control measures. Here, we investigate awareness of infection and symptoms in relation to antibodies against SARS-CoV-2 in healthy plasma donors. We asked individuals donating plasma across the Netherlands between May 11 th and 18 th 2020 to report COVID-19-related symptoms, and we tested for antibodies indicative of a past infection with SARS-CoV-2. Among 3,676 with antibodies, and from questionnaire data, 239 (6.5%) are positive for SARS-CoV-2 antibodies. Of those, 48% suspect no COVID-19, despite the majority reporting symptoms; 11% of seropositive individuals report no symptoms and 27% very mild symptoms at any time during the first peak of the epidemic. Anosmia/ageusia and fever are most strongly associated with seropositivity. Almost half of seropositive individuals do not suspect SARS-CoV-2 infection. Improved recognition of COVID-19 symptoms, in particular, anosmia/ageusia and fever, is needed to reduce widespread SARS-CoV-2 transmission. Competing Interests: The authors declare no competing interests. (© 2021 The Author(s).)
Databáze:	MEDLINE
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