Evidence for multiple cases of recurrent Legionella infection: a Danish national surveillance study.

Autor: Cassell K; Epidemiology of Microbial Diseases, Yale University School of Public Health, New Haven, Connecticut, USA kelsie.cassell@yale.edu., Kjelsø C; Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark., Weinberger DM; Epidemiology of Microbial Diseases, Yale University School of Public Health, New Haven, Connecticut, USA., Uldum SA; Department of Bacteria, Parasites & Fungi, Statens Serum Institut, Copenhagen, Denmark.
Jazyk: angličtina
Zdroj: Thorax [Thorax] 2021 Jan 27. Date of Electronic Publication: 2021 Jan 27.
DOI: 10.1136/thoraxjnl-2020-216344
Abstrakt: While case reports have documented recurrence of Legionnaires' disease, the frequency of recurrent infections has not been systematically examined at a national level over multiple decades. Between 2000 and 2020 in Denmark, 21 individuals had repeat laboratory-identified Legionella infection, totalling 48 episodes of hospitalisation. The majority of these individuals had underlying comorbidities. In at least 3 of the 21 cases, a different Legionella serogroup was detected during the second episode of infection, which could indicate reinfection from a new source. These results emphasise that Legionella can, and does, reinfect high-risk individuals causing multiple hospitalisations.
Competing Interests: Competing interests: None declared.
(© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze: MEDLINE