Analysis of 3702 patients with acne vulgaris and concomitant comorbidities in Turkey: a multi-centered, prospective, controlled study.

Autor: Ünal E; Department of Dermatology, Lokman Hekim University, Private Akay Hospital, Ankara, Turkey., Karadağ AS; Department of Dermatology, Memorial Atasehir Hospital, Istanbul, Turkey., Şikar Aktürk A; Department of Dermatology, School of Medicine, Kocaeli University, Kocaeli, Turkey., Dizen Namdar N; Department of Dermatology, Kutahya University of Health Sciences Faculty of Medicine, Kutahya, Turkey., Kelekçi KH; Department of Dermatology, Izmir Katip Çelebi University School of Medicine, Izmir, Turkey., Aksoy B; Department of Dermatology, Faculty of Medicine, Bahcesehir University, Istanbul, Turkey., Özlü E; Department of Dermatology, Duzce University School of Medicine, Duzce, Turkey., Baykal L; Department of Dermatology, Karadeniz Technical University School of Medicine, Trabzon, Turkey., Karaman G; Department of Dermatology, Karaman G. Private Clinic, Aydın, Turkey., Sarıcaoğlu H; Department of Dermatology, Uludag University School of Medicine, Bursa, Turkey., Zindancı İ; Umraniye Education and Research Hospital, Health Sciences University, Istanbul, Turkey., Balta İ; Ankara Training and Research Hospital, Health Sciences University, Ankara, Turkey., Turan Ç; Ankara Training and Research Hospital, Health Sciences University, Ankara, Turkey., Can Kuru B; Bakırkoy Education and Research Hospital, Health Sciences University, Istanbul, Turkey.
Jazyk: angličtina
Zdroj: International journal of dermatology [Int J Dermatol] 2021 May; Vol. 60 (5), pp. 597-604. Date of Electronic Publication: 2021 Jan 20.
DOI: 10.1111/ijd.15406
Abstrakt: Background: Acne vulgaris is a chronic inflammatory skin disease that affects the pilosebaceous unit. Although it is considered to be a skin-limited disease, different clinical studies have recently been published in which the disease is accompanied by systemic symptoms. In this study, systemic comorbidities accompanying acne vulgaris and the relationship between existing comorbidities and disease severity are investigated.
Methods: This prospective multicenter study was conducted by the Turkish Society of Dermatology Acne Study Group. Twelve dermatology clinics and 14 clinicians throughout Turkey participated in the study. A structured physician-administered questionnaire was used to collect patient demographics, clinical findings, and lifestyle data. Physicians recorded each participant's medical history, including current and past comorbidities, duration of any comorbidity, smoking, and drinking. Body mass index (BMI) was calculated.
Results: There were 3022 patients in the adolescent acne group and 897 in the control group. The incidence of nonmigraine headache in adolescents with acne was significantly higher than in the nonacne group (P = 0.019). There were 680 patients in the postadolescent acne group and 545 in the control group. In the postadolescent group, incidence of metabolic disease was lower than the control group (P = 0.003). In the postadolescent group, premenstrual syndrome (P < 0.001) and PCOS (P = 0.007) were more common than the control group.
Conclusions: In this study, we observed that acne vulgaris does not cause systemic comorbidities. There is also a need for new studies involving a large number of patients to illuminate systemic diseases accompanying acne vulgaris.
(© 2021 the International Society of Dermatology.)
Databáze: MEDLINE
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