[Arterial stiffness in patients with acute cerebrovascular accident].

Autor:	Trush EY; Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia., Ivanova SV; Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia., Savin AA; Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia., Yushchuk EN; Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia., Teltevskaya II; Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia., Melehina IV; Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia., Dobrovolskaya LE; Municipal Clinical Hospital Br. Bahrushins of the Health Care Department of Moscow City, Moscow, Russia.
Jazyk:	ruština
Zdroj:	Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova [Zh Nevrol Psikhiatr Im S S Korsakova] 2020; Vol. 120 (12. Vyp. 2), pp. 16-21.
DOI:	10.17116/jnevro202012012216
Abstrakt:	Objective: To identify correlations between parameters of vascular stiffness and characteristics of the clinical course of acute cerebrovascular accident (stroke). Material and Methods: Two hundred and seven patients with stroke (mean age 64.6±10.9 years; 115 men) treated in a neurological department of «Municipal Clinical Hospital Br. Bakhrushins of the Health Care Department of Moscow» were studied. All patients underwent a standard neurological and clinical-instrumental examination, including assessment of arterial stiffness by sphygmography. Analysis of the data was carried out depending on the severity of stroke and the pathogenetic subtype of stroke. Results: The pathological value of the CAVI was detected in all patients with cerebral infarction. The highest values were noted in patients with an atherothrombotic subtype of stroke. A positive correlation was revealed between CAVI and the age of patients ( r =0.57; p =0.0001), left ventricular myocardial mass index ( r =0.55; p =0.0001), NIHSS score ( r =0.6; p =0.0001) The inverse correlation was found between CAVI and glomerular filtration rate ( r = -0.4; p =0.02). Conclusions: The factors determining the severity of stroke are age, arterial hypertension, type 2 diabetes, carotid atherosclerosis, left ventricular remodeling, and decreased glomerular filtration rate. The CAV and the toe-brachial index, rather than the ankle-brachial index, significantly distinguished patients with ischemic stroke from patients with transient ischemic attack.
Databáze:	MEDLINE
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