Iso-octenidine: Promising Octenidine Analogue with Improved Solubility.
| Autor: | Yakuschenko IK; Institute of Problems of Chemical Physics of the Russian Academy of Sciences, 142432 Chernogolovka, Moscow Region, Russian Federation., Pozdeeva NN; Institute of Problems of Chemical Physics of the Russian Academy of Sciences, 142432 Chernogolovka, Moscow Region, Russian Federation., Mumyatova VA; Institute of Problems of Chemical Physics of the Russian Academy of Sciences, 142432 Chernogolovka, Moscow Region, Russian Federation., Terentiev AA; Institute of Problems of Chemical Physics of the Russian Academy of Sciences, 142432 Chernogolovka, Moscow Region, Russian Federation., Gadomsky SY; Institute of Problems of Chemical Physics of the Russian Academy of Sciences, 142432 Chernogolovka, Moscow Region, Russian Federation. |
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| Jazyk: | angličtina |
| Zdroj: | Current organic synthesis [Curr Org Synth] 2021; Vol. 18 (5), pp. 443-445. |
| DOI: | 10.2174/1570179417666201231104453 |
| Abstrakt: | Iso-octenidine, an isomer of octenidine dihydrochloride, was synthesized and studied for the first time. Iso-octenidine was demonstrated to be 3-fold more soluble in water in comparison to original octenidine, and both substances had remarkably similar antibacterial activity (tested on Escherichia Coli and Micrococcus luteus). (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.) |
| Databáze: | MEDLINE |
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