Continuous Glucose Monitoring in the Intensive Care Unit During the COVID-19 Pandemic.

Autor: Agarwal S; Fleischer Institute for Diabetes and Metabolism, New York Regional Center for Diabetes Translation Research, Albert Einstein College of Medicine, Bronx, NY shivani.agarwal@einsteinmed.org.; Montefiore Medical Center, Bronx, NY., Mathew J; Montefiore Medical Center, Bronx, NY., Davis GM; Division of Endocrinology, Metabolism, and Lipids, Department of Medicine, Emory University School of Medicine, Atlanta, GA., Shephardson A; Montefiore Medical Center, Bronx, NY., Levine A; Montefiore Medical Center, Bronx, NY., Louard R; Fleischer Institute for Diabetes and Metabolism, New York Regional Center for Diabetes Translation Research, Albert Einstein College of Medicine, Bronx, NY.; Montefiore Medical Center, Bronx, NY., Urrutia A; Division of Endocrinology, Metabolism, and Lipids, Department of Medicine, Emory University School of Medicine, Atlanta, GA., Perez-Guzman C; Division of Endocrinology, Metabolism, and Lipids, Department of Medicine, Emory University School of Medicine, Atlanta, GA., Umpierrez GE; Division of Endocrinology, Metabolism, and Lipids, Department of Medicine, Emory University School of Medicine, Atlanta, GA., Peng L; Division of Endocrinology, Metabolism, and Lipids, Department of Medicine, Emory University School of Medicine, Atlanta, GA., Pasquel FJ; Division of Endocrinology, Metabolism, and Lipids, Department of Medicine, Emory University School of Medicine, Atlanta, GA.
Jazyk: angličtina
Zdroj: Diabetes care [Diabetes Care] 2021 Mar; Vol. 44 (3), pp. 847-849. Date of Electronic Publication: 2020 Dec 23.
DOI: 10.2337/dc20-2219
Abstrakt: Objective: Real-time continuous glucose monitoring (rtCGM) in critically ill hospitalized patients holds promise; however, real-world data are needed.
Research Design and Methods: We placed Dexcom G6 CGM on intensive care unit (ICU) patients at Montefiore Medical Center with confirmed coronavirus disease 2019 (COVID-19) infection and glycemic variability. We analyzed inpatient CGM accuracy using point-of-care (POC) glucose-CGM matched pairs and included patients for analysis regardless of clinical status.
Results: We included 11 patients with CGM: 8 on continuous insulin infusion (CII), 8 on vasopressors, 8 intubated, 4 on high-dose glucocorticoids, 6 on renal replacement therapy, and 2 with anasarca. Accuracy was 12.58% for mean and 6.3% for median absolute relative difference. CGM reduced POC testing by ∼60% for patients on CII.
Conclusions: In this real-world preliminary analysis of rtCGM during critical illness, we demonstrate early feasibility, considerable accuracy, and meaningful reduction in the frequency of POC glucose testing.
(© 2020 by the American Diabetes Association.)
Databáze: MEDLINE