Micronucleus Evaluation in Exfoliated Human Buccal Epithelium Cells among E-Waste Workers in Payatas, the Philippines.

Autor:	Berame JS; Education/Biology Department, Caraga State University, Butuan City, Philippines.; Biology Department, De La Salle University, Manila, Philippines., Lapada AA; Education Department, Eastern Samar State University, Borongan City, Philippines.; Biology Department, De La Salle University, Manila, Philippines., Miguel FF; Science and Technology Department, Ramon Magsaysay High School, Manila, Philippines.; Biology Department, De La Salle University, Manila, Philippines., Noguera EC; Science Department, Manuel Roxas High School, Manila, Philippines.; Biology Department, De La Salle University, Manila, Philippines., Alam ZF; Biology Department, De La Salle University, Manila, Philippines.
Jazyk:	angličtina
Zdroj:	Journal of health & pollution [J Health Pollut] 2020 Dec 07; Vol. 10 (28), pp. 201213. Date of Electronic Publication: 2020 Dec 07 (Print Publication: 2020).
DOI:	10.5696/2156-9614-10.28.201213
Abstrakt:	Background: The improper recycling of electronic waste (e-waste) by informal recyclers often leads to contamination of the environment. E-waste contains organic and inorganic compounds along with heavy metals and trace elements. These pollutants can have a negative effect on humans. Biomonitoring can provide information on the sources, amount, geographical distribution, and adverse health effects of contaminants. Objectives: The present study aimed to assess risks to the health of informal e-waste recyclers in Payatas, the Philippines due to their exposure to e-waste toxicity by examining the presence of micronuclei in buccal epithelium cells. Methodology: Frequencies of binucleated cells (BNc) and abnormal cells were obtained from the buccal epithelium of the study population composed of e-waste exposed recyclers (n=40) and a control group (n=52). Descriptive statistics and regression analysis were employed for the data analysis. Results: Participants' gender, occupation, smoking status, alcohol consumption, and the number of karyolitic cells of both groups were significantly associated. Only occupation in e-waste recycling and length of e-waste exposure were significantly associated in terms of the number of abnormal cells and micronuclei. Similar trends were found in the linear regression analysis drawn from participants' length of e-waste exposure with a significance of R 2 = 7346, indicating that as the length of e-waste exposure increased, the number of micronuclei found in the participants' buccal epithelium cells increased as well. Conclusions: Longer exposure to e-waste materials may induce genotoxic damage in human cells which is a serious concern, leading to adverse effects to human health. Competing Interests: The authors declare no competing financial interests. (© Pure Earth 2020.)
Databáze:	MEDLINE
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