Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) universal screening in gravids during labor and delivery.

Autor: Savirón-Cornudella R; Department of Obstetrics and Gynecology, Hospital Universitario General de Villalba, Madrid, Spain. Electronic address: ricardo.saviron@hgvillalba.es., Villalba A; Department of Obstetrics and Gynecology, Hospital Universitario General de Villalba, Madrid, Spain., Zapardiel J; Department of Microbiology, Hospital Universitario General de Villalba, Madrid, Spain., Andeyro-Garcia M; Department of Obstetrics and Gynecology, Hospital Universitario General de Villalba, Madrid, Spain., Esteban LM; Escuela Universitaria Politécnica de La Almunia, Universidad de Zaragoza, Zaragoza, Spain., Pérez-López FR; Instituto de Investigación Sanitaria de Aragón and University of Zaragoza, Faculty of Medicine, Zaragoza, Spain.
Jazyk: angličtina
Zdroj: European journal of obstetrics, gynecology, and reproductive biology [Eur J Obstet Gynecol Reprod Biol] 2021 Jan; Vol. 256, pp. 400-404. Date of Electronic Publication: 2020 Dec 01.
DOI: 10.1016/j.ejogrb.2020.11.069
Abstrakt: Objective: To screen pregnant women at risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during delivery using reverse-transcription polymerase chain reaction (RT-PCR) test and serum immunoglobulin (Ig) testing.
Method: Between March 31 st and August 31 st of 2020, consecutive pregnant women admitted for labor and delivery in a single hospital were screened for SARS-CoV-2 with nasopharyngeal RT-PCR swab tests and detection of serum IgG and IgM.
Results: We studied 266 pregnant women admitted for labor and delivery. The prevalence of acute or past SARS-CoV-2 infection was 9.0 %, including (i) two cases with respiratory symptoms of SARS-Co-V-2 infection and positive RT-PCR; (ii) four asymptomatic women with positive RT-PCR without clinical symptoms and negative serological tests between two and 15 weeks later; and (iii) two women with false positive RT-PCR due to technical problems. All newborns of the 6 pregnant women with RT-PCR positive had negative RT-PCR and did not require Neonatal Intensive Care Unit admission. There were eighteen asymptomatic women with positive serological IgG tests and negative RT-PCR.
Conclusion: In our cohort of gravids, we found 2.2 % of women with positive RT-PRC tests and 6.7 % with positive serological tests during the first wave of the SARS-CoV-2 pandemic.
Competing Interests: Declaration of Competing Interest The authors report no conflicts of interest and are alone responsible for the content and the writing of the article.
(Copyright © 2020 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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