Non-sebaceous lymphadenoma of the submandibular gland: diagnostic challenges in the head and neck cancer pathway.

Autor: Garside G; York Hospitals NHS Trust, York, North Yorkshire, UK., Jaikaransingh D; St George's University of London, London, London, UK., Pitiyage G; Pathology, St George's University Hospital NHS Foundation Trust, London, London, UK., Ofo E; ENT-Head & Neck Surgery, St George's University Hospital NHS Foundation Trust, London, London, UK enyinnaya.ofo@stgeorges.nhs.uk.
Jazyk: angličtina
Zdroj: BMJ case reports [BMJ Case Rep] 2020 Nov 30; Vol. 13 (11). Date of Electronic Publication: 2020 Nov 30.
DOI: 10.1136/bcr-2020-238099
Abstrakt: Non-sebaceous lymphadenoma (NSLA) is a rare benign salivary gland tumour with lymphoid and epithelial components and without sebaceous differentiation. The large majority of the reported cases arise within the parotid gland. We present an NSLA arising from the submandibular gland. The tumour presented as a painless longstanding neck lump. Ultrasound, fine needle aspiration, MRI and positron emission tomography found features supportive of squamous cell carcinoma. The patient was treated with surgery for oropharyngeal carcinoma of unknown origin, in accordance with local and national guidelines. The final histological assessment revealed the level Ib neck lesion to be NSLA. Although a rare occurrence, these lesions may pose a diagnostic challenge in the head and neck cancer pathway.
Competing Interests: Competing interests: None declared.
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Databáze: MEDLINE