When Frequent (Pandemic) Occurs in a Non-Frequent Disease: COVID-19 and Fabry Disease: Report of Two Cases.

Autor: Gómez-Luján M; Department of Nephrology, Edgardo Rebagliati Martins National Hospital, Peru.; Federico Villarreal National University, Peru., Cruzalegui C; Department of Nephrology, Edgardo Rebagliati Martins National Hospital, Peru., Aguilar C; Pathology Laboratory, Cardiovascular National Institute, Peru.; Department of Cardiology Research, Torres de Salud National Research Center, Peru., Alvarez-Vargas M; Department of Internal Medicine, Guillermo Almenara Irigoyen National Hospital, Peru.; Department of Cardiology Research, Torres de Salud National Research Center, Peru., Segura-Saldaña P; Department of Cardiology Research, Torres de Salud National Research Center, Peru.; Department of Cardiology, Edgardo Rebagliati Martins National Hospital, Peru.; Biomedical Engineering, Universidad Peruana Cayetano Heredia, Peru.
Jazyk: angličtina
Zdroj: Japanese journal of infectious diseases [Jpn J Infect Dis] 2021 May 24; Vol. 74 (3), pp. 228-232. Date of Electronic Publication: 2020 Nov 30.
DOI: 10.7883/yoken.JJID.2020.729
Abstrakt: Fabry disease (FD), like COVID-19, can affect multiple organs, including the lungs. Patients with FD are expected to develop severe COVID-19, due to involvement of not only the lungs but also the kidneys and the presence of other comorbidities. We present 2 cases of mild COVID-19 in patients with FD who were infected with the COVID-19 virus. Although it is unknown whether the X chromosome mutation in patients with FD affects the development of severe COVID-19, it is suggested that it may play a protective role against COVID-19 infection. Based on these cases, we suggest that FD is not a risk factor for severe COVID-19.
Databáze: MEDLINE