Comparative analysis of the impact of blood collection systems on the results of the study of indicators hemostasis system.

Autor:	Petrova OV; Federal state budgetary establishment «Federal center cardiovascular surgery» (Astrakhan).; Astrakhan State Medical University., Dymova OV; Federal state budgetary scientific institution «Petrovsky national research center of surgery»., Tverdokhlebova DK; Federal state budgetary establishment «Federal center cardiovascular surgery» (Astrakhan)., Smeltsova EV; Federal state budgetary establishment «Federal center cardiovascular surgery» (Astrakhan)., Panova EV; Federal state budgetary establishment «Federal center cardiovascular surgery» (Astrakhan)., Nikulina DM; Astrakhan State Medical University.
Jazyk:	angličtina
Zdroj:	Klinicheskaia laboratornaia diagnostika [Klin Lab Diagn] 2020 Sep 17; Vol. 65 (10), pp. 607-610.
DOI:	10.18821/0869-2084-2020-65-10-607-610
Abstrakt:	Comparative analysis of the impact of blood collection systems on the results of routine coagulation tests. The aim of this study was to conduct comparative analysis of the effects of blood collection systems on the results of routine coagulation tests. The study involved practically healthy women over 18 years of age female (n=30). Inclusion criteria: practically healthy individuals. Exclusion criteria: taking non-steroidal anti-inflammatory drugs, or oral contraceptives. Blood collection was carried out in the following systems: 1 system-Vacuette Premium,2 system- Improvacuter, 3 system- BD Vacutainer® Plus. Before and after centrifugation, visual assessment of tubes was performed.No signs for the presence of clots, hemolysis, or insufficient filling was observed. In each sample we measured prothrombin time (PV, sec), activated partial thromboplastin time (APTT, sec), and fibrinogen (F, g/l) by clotting method on the automatic coagulometer «Sta Compact» («Diagnostica Stago», France). The results of laboratory analyses were processed using parametric and non - parametric statistics using The Statistica 12.0 software. At the preanalytical laboratory stage, there were no differences when using systems for blood sampling: the clots and hemolysis were not detected in the samples, the level of filling of the sistems was sufficient. Comparative analysis revealed small, though statistically significant, differences for: PT when comparing Improvacuter wiht Vacuette Premium or BD Vacutainer®; APPT when comparing Improvacuter wiht Vacuette Premium. No differences were observed for Fg levels. Our results support the data available in the literature on the effects of blood-taking systems on hemostasis , which should be taken into account when purchasing blood collection systems. Competing Interests: The authors declare no conflict of interest.
Databáze:	MEDLINE
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