Sonographic findings in visceral leishmaniasis - A narrative review.

Autor: Bélard S; Department of Pediatric Pulmonology, Immunology and Intensive Care Medicine, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany; Berlin Institute of Health, Anna-Louisa-Karsch-Straße 2, 10178, Berlin, Germany. Electronic address: sabine.belard@charite.de., Stratta E; Médecins Sans Frontières, 40 Rector St., 16th Floor, New York, NY, 10006, USA. Electronic address: erin.stratta@newyork.msf.org., Zhao A; Médecins Sans Frontières, 40 Rector St., 16th Floor, New York, NY, 10006, USA. Electronic address: amelia.zhao@newyork.msf.org., Ritmeijer K; Médecins Sans Frontières, Plantage Middenlaan 14, 1018 DD, Amsterdam, the Netherlands. Electronic address: koert.ritmeijer@amsterdam.msf.org., Moretó-Planas L; Médecins Sans Frontières, Medical Department, Carrer Zamora 54, Barcelona, 08005, Spain. Electronic address: laura.moreto@barcelona.msf.org., Fentress M; London School of Hygiene and Tropical Medicine, Keppel St, Bloomsbury, London, WC1E 7HT, UK; Johns Hopkins University, Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD, 21205, USA; University of California, Davis, 4860 Y St., Suite 2300, Sacramento, CA 95817, USA. Electronic address: mfentress2010@gmail.com., Nadimpalli A; Médecins Sans Frontières, 40 Rector St., 16th Floor, New York, NY, 10006, USA. Electronic address: adi.nadimpalli@newyork.msf.org., Grobusch MP; Center of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Amsterdam Public Health, Amsterdam Infection & Immunity, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Meibergdreef 9, PO Box 22660, 1100 DD, Amsterdam, the Netherlands. Electronic address: m.p.grobusch@amc.uva.nl., Heller T; Lighthouse Clinic, Kamuzu Central Hospital, Kamuzu Central Hospital Area 33 Mzimba Street, P.O. Box 106, Lilongwe, Malawi. Electronic address: echnatom@web.de., Heuvelings CC; Center of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Amsterdam Public Health, Amsterdam Infection & Immunity, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Meibergdreef 9, PO Box 22660, 1100 DD, Amsterdam, the Netherlands. Electronic address: lotjeh@hotmail.com.
Jazyk: angličtina
Zdroj: Travel medicine and infectious disease [Travel Med Infect Dis] 2021 Jan-Feb; Vol. 39, pp. 101924. Date of Electronic Publication: 2020 Nov 21.
DOI: 10.1016/j.tmaid.2020.101924
Abstrakt: Background: Visceral leishmaniasis (VL) is predominantly a neglected tropical parasitic disease but may also be acquired by travellers. We aimed at summarizing knowledge on sonographic presentation of VL to better understand sonographic features of VL.
Methods: PubMed was searched for studies and case reports presenting original data on sonographic findings of VL, published before August 13th, 2019. Demographic, clinical, and sonographic data were extracted and summarized in a qualitative approach.
Results: A total of 36 publications were included in this review; 27 of these were case reports and the remainder were prospective or retrospective studies. No study reported systematic cross-sectional comparative imaging. Overall, publications reported on 512 patients with VL of whom 12 were reported HIV-infected. Spleno- and hepatomegaly were the most frequently reported findings. Further relevant and repeatedly reported findings were splenic and hepatic lesions, abdominal lymphadenopathy, pleural and pericardial effusion and ascites. Reported focal splenic lesions were heterogeneous in size, shape, and echogenicity. Several publications reported gradual diminution and resolution of sonographic findings with VL treatment.
Conclusion: Available literature on sonographic findings of VL is limited. Available reports indicate that spleno- and hepatomegaly, free fluid, abdominal lymphadenopathy, and focal splenic lesions may be common sonographic features in patients with VL. Because of the apparent overlap of sonographic features of VL, extrapulmonary tuberculosis and other conditions, interpretation of sonographic findings needs to be made with particular caution.
(Copyright © 2020 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: