Hepatitis B-related hepatocellular carcinoma in a 36-year-old pregnant woman: prognosis and management dilemma.
| Autor: | Wembulua BS; Department of Infectious and Tropical Diseases, Fann University Hospital, Dakar, Senegal., Diallo K; Unit of Infectious and Tropical Diseases, Assane Seck University, Hospital de la Paix, Ziguinchor, Senegal., Thioubou MA; Unit of Gastroenterology and Hepatology, Hospital de la Paix, Ziguinchor, Senegal., Nguma JDB; Department of Obstetrics and Gynecology, Kisangani University Hospital, Democratic Republic of the Congo., Manga NM; Unit of Infectious and Tropical Diseases, Assane Seck University, Hospital de la Paix, Ziguinchor, Senegal. |
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| Jazyk: | angličtina |
| Zdroj: | The Pan African medical journal [Pan Afr Med J] 2020 Aug 18; Vol. 36, pp. 298. Date of Electronic Publication: 2020 Aug 18 (Print Publication: 2020). |
| DOI: | 10.11604/pamj.2020.36.298.22658 |
| Abstrakt: | Management of chronic hepatitis B infection complicated by hepatocellular carcinoma (HCC) in pregnancy poses a treatment dilemma as the pregnancy accelerates disease progression and narrows the diagnostic tools and therapeutic choices. Studies have reported higher maternal and fetal losses. We share our experience with a 36-year-old pregnant woman who presented at 35 weeks' gestation with a large painful nodular liver and significant weight loss. She tested HBsAg-positive and had both clinical and laboratory features of severe liver decompensation. The abdominal ultrasound rightly described HCC on a cirrhotic background. The fetus was delivered by cesarean section but the mother died soon after. Competing Interests: The authors declare no competing interests. (Copyright: Bruce Shinga Wembulua et al.) |
| Databáze: | MEDLINE |
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