Muscle Echogenicity and Changes Related to Age and Body Mass Index.

Autor: Pereira AZ; Endocrinology Division, UNIFESP, São Paulo, Brazil.; Oncology and Hematology Department, Hospital Israelita Albert Einstein, S. Paulo, São Paulo, Brazil., Uezima CB; Endocrinology Division, UNIFESP, São Paulo, Brazil., Zanella MT; Endocrinology Division, UNIFESP, São Paulo, Brazil., Prado RRD; Endocrinology Division, UNIFESP, São Paulo, Brazil., Gonzalez MC; Post-graduation Program on Health and Behavior, Catholic University of Pelotas, Pelotas, Brazil., Zheng J; Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana, USA., Heymsfield SB; Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana, USA.
Jazyk: angličtina
Zdroj: JPEN. Journal of parenteral and enteral nutrition [JPEN J Parenter Enteral Nutr] 2021 Sep; Vol. 45 (7), pp. 1591-1596. Date of Electronic Publication: 2020 Dec 08.
DOI: 10.1002/jpen.2030
Abstrakt: Introduction: Muscle fibers are lost and replaced by fat- and fibrous-tissue infiltration during aging. This process decreases muscle quality and influences tissue appearance on ultrasound images over time. Increased muscle "echogenicity" represents changes caused by fat- and fibrous-tissue infiltration and can be quantified with recently developed software.
Objective: To investigate skeletal muscle quality through echogenicity, estimates according to participant's body mass index (BMI) and age were taken.
Methods: This was a cross-sectional study performed at the Pennington Biomedical Research Center, Baton Rouge, Louisiana with 117 participants (57 men and 60 women), with mean age (±SD) 38.9 ± 17.0 years and BMI 28.6 ± 6.2 kg/m². All participants were examined by ultrasound (LOGIQ GE Healthcare), using a 5.0-MHz linear transducer. Participants had muscle thickness measured by ultrasound at 4 anatomic locations (biceps and triceps brachial, femoral quadriceps, and calf triceps). Echogenicity was analyzed with specific software (Pixel Health) that evaluated the image in gray scale.
Results: According to BMI, 41% of participants were obese. There was a positive correlation between age and thigh-muscle echogenicity (r p = 0.534, P < .0001) and a negative correlation between thigh-muscle echogenicity and thickness (r p = -0.395, P <.0001). There was high muscle echogenicity in participants with overweight and obesity aged 50 years or older (P < .05).
Conclusion: Older age and higher BMI were associated with stronger echogenicity signals and smaller muscle thickness. People with overweight, obesity, and/or older than 50 years old have reduced muscle quality with smaller muscle thickness, as observed with ultrasound.
(© 2020 American Society for Parenteral and Enteral Nutrition.)
Databáze: MEDLINE
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