Viscoelastic testing in benign hematologic disorders: Clinical perspectives and future implications of point-of-care testing to assess hemostatic competence.

Autor: Speybroeck J; Indiana University School of Medicine, Notre Dame Campus, South Bend, Indiana., Marsee M; Indiana University School of Medicine, Notre Dame Campus, South Bend, Indiana., Shariff F; Saint Joseph Regional Medical Center, Mishawaka, Indiana., Zackariya N; Saint Joseph Regional Medical Center, Mishawaka, Indiana., Grisoli A; Indiana University School of Medicine, Notre Dame Campus, South Bend, Indiana., Lune SV; Indiana University School of Medicine, Notre Dame Campus, South Bend, Indiana., Larson EE; Indiana University School of Medicine, Notre Dame Campus, South Bend, Indiana., Hatch J; Indiana University School of Medicine, Notre Dame Campus, South Bend, Indiana., McCauley R; Indiana University School of Medicine, Notre Dame Campus, South Bend, Indiana., Shariff F; Indiana University School of Medicine, Notre Dame Campus, South Bend, Indiana., Aversa JG; Department of General Surgery, Indiana University School of Medicine, Indianapolis, Indiana., Son M; Saint Joseph Regional Medical Center, Mishawaka, Indiana., Agostini V; Department of Transfusion Medicine, IRCC Polyclinic Hospital San Marino, Genoa, Italy., Campello E; Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, Padua University Hospital, Padua, Italy., Simioni P; Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, Padua University Hospital, Padua, Italy., Scărlătescu E; Department of Anaesthesia and Intensive Care, Fundeni Clinical Institute, Bucharest, Romania., Kwaan H; Department of Hematology Oncology, Northwestern University School of Medicine, Chicago, Illinois., Hartmann J; Department of Medical Affairs, Haemonetics Corporation, Boston, Massachusetts., Fries D; Department of General and Surgical Critical Care Medicine, Medical University of Innsbruck, Innsbruck, Austria., Walsh M; Indiana University School of Medicine, Notre Dame Campus, South Bend, Indiana.; Saint Joseph Regional Medical Center, Mishawaka, Indiana.
Jazyk: angličtina
Zdroj: Transfusion [Transfusion] 2020 Oct; Vol. 60 Suppl 6, pp. S101-S121.
DOI: 10.1111/trf.16088
Abstrakt: Viscoelastic tests (VETs) have been used routinely for liver transplantation, cardiac surgery, and trauma, but only recently have found clinical utility in benign hematologic disorders. Therefore, guidelines for diagnosis and treatment of these disorders based on viscoelastic variables have been adapted from the existing transplant, cardiothoracic surgery, and trauma resuscitation literature. As a result, diagnostic and therapeutic strategies for benign hematologic disorders utilizing VETs are not uniform. Accordingly, even though there has been a recent increase in the utilization of VET for the diagnosis and treatment of such disorders, the literature is still in its early stages. Analysis of point-of-care viscoelastic tracings from benign hematologic disorders has the potential to allow prompt recognition of disease and to guide patient-specific intervention. Here we present a review describing the application of VETs to benign hematologic disorders.
(© 2020 AABB.)
Databáze: MEDLINE
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