Surgical resection, intraoperative radiotherapy and immediate plastic reconstruction: A good option for the treatment of distal extremity soft tissue sarcomas.

Autor:	Hanna SA; Radiation Oncologist at Hospital Sírio-Libanês, rua dona Adma Jafet 91, Cerqueira Cesar, São Paulo, SP, 01308-050 Brazil., Munhoz RR; Medical Oncologist at Hospital Sírio-Libanês, rua dona Adma Jafet 91, Cerqueira Cesar, São Paulo, SP, 01308-050 Brazil., de Freitas Perina AL; Surgical Oncologist at Hospital Sírio-Libanês, rua dona Adma Jafet 91, Cerqueira Cesar, São Paulo, SP, 01308-050 Brazil., Gonçalves MS; Medical Oncologist at Hospital Sírio-Libanês, rua dona Adma Jafet 91, Cerqueira Cesar, São Paulo, SP, 01308-050 Brazil., da Costa FPP; Plastic Surgeon at Hospital Sírio-Libanês, rua dona Adma Jafet 91, Cerqueira Cesar, São Paulo, SP, 01308-050 Brazil., de Freitas Busnardo F; Surgical Oncologist at Hospital Sírio-Libanês, rua dona Adma Jafet 91, Cerqueira Cesar, São Paulo, SP, 01308-050 Brazil., de Oliveira Ferreira F; Plastic Surgeon at Hospital Sírio-Libanês, rua dona Adma Jafet 91, Cerqueira Cesar, São Paulo, SP, 01308-050 Brazil.
Jazyk:	angličtina
Zdroj:	Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology [Rep Pract Oncol Radiother] 2020 Nov-Dec; Vol. 25 (6), pp. 919-926. Date of Electronic Publication: 2020 Oct 03.
DOI:	10.1016/j.rpor.2020.09.008
Abstrakt:	Aim: To show three patients with soft tissue sarcomas of distal extremities conservatively treated after tumor-board discussion, involving margin-free surgery, exclusive intraoperative radiotherapy, and immediate reconstruction. Background: Current guidelines show clear and robust recommendations regarding the composition of the treatment of sarcomas of extremities. However, little evidence exists regarding the application of these treatments depending on the location of the primary neoplasia. Tumors that affect the distal extremities present different challenges and make multidisciplinary discussions desirable. Methods/results: We reported 3 patients who were approached with a conservative intention, after tumor board recomendation. The goals from the treatment performed were aesthetic and functional preservation, while enruring locoregional control. We had wound healing complications in 2 of the cases, requiring additional reconstruction measures. Patients are followed up for 24, 20 and 10 months; local control is 100%, and functional preservation is 100%. Conclusions: Despite being a small series, it was sufficient to illustrate successful multidisciplinary planning, generating a therapeutic result with improved quality of life for patients who had an initial indication for extremity amputation. (© 2020 Greater Poland Cancer Centre. Published by Elsevier B.V. All rights reserved.)
Databáze:	MEDLINE
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