Evaluation of viral co-infections among patients with community-associated Clostridioides difficile infection.

Autor: Korhonen L; Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, United States of America., Cohen J; Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.; Atlanta Research and Education Foundation, Atlanta, Georgia, United States of America., Gregoricus N; Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America., Farley MM; Emory University School of Medicine, Atlanta, Georgia, United States of America.; Veterans Affairs Medical Center, Atlanta, Georgia, United States of America., Perlmutter R; Maryland Department of Health, Baltimore, Maryland, United States of America., Holzbauer SM; Minnesota Department of Health, St Paul, Minnesota, United States of America.; Career Epidemiology Field Officer Program, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America., Dumyati G; New York Emerging Infections Program and University of Rochester Medical Center, Rochester, New York, United States of America., Beldavs Z; Oregon Health Authority, Portland, Oregon, United States of America., Paulick A; Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, United States of America., Vinjé J; Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America., Limbago BM; Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, United States of America., Lessa FC; Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, United States of America., Guh AY; Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2020 Oct 19; Vol. 15 (10), pp. e0240549. Date of Electronic Publication: 2020 Oct 19 (Print Publication: 2020).
DOI: 10.1371/journal.pone.0240549
Abstrakt: We assessed viral co-infections in 155 patients with community-associated Clostridioides difficile infection in five U.S. sites during December 2012-February 2013. Eighteen patients (12%) tested positive for norovirus (n = 10), adenovirus (n = 4), rotavirus (n = 3), or sapovirus (n = 1). Co-infected patients were more likely than non-co-infected patients to have nausea or vomiting (56% vs 31%; p = 0.04), suggesting that viral co-pathogens contributed to symptoms in some patients. There were no significant differences in prior healthcare or medication exposures or in CDI complications.
Competing Interests: No authors have competing interests.
Databáze: MEDLINE
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