Mobility improvement of patients with peripheral visual field losses using novel see-through digital spectacles.

Autor: Sayed AM; Biomedical Engineering Department, Helwan University, Helwan, Egypt.; Bascom Palmer Eye Institute, University of Miami, Miami, FL, United States of America.; Electrical Engineering and Computer Science, MSOE University, Milwaukee, WI, United States of America., Shousha MA; Bascom Palmer Eye Institute, University of Miami, Miami, FL, United States of America.; Department of Electrical and Computer Engineering, University of Miami, Miami, FL, United States of America.; Biomedical Engineering Department, University of Miami, Miami, FL, United States of America., Baharul Islam MD; Bascom Palmer Eye Institute, University of Miami, Miami, FL, United States of America.; Department of Computer Science, American University of Malta, BML, Malta., Eleiwa TK; Bascom Palmer Eye Institute, University of Miami, Miami, FL, United States of America.; Faculty of Medicine, Department of Ophthalmology, Benha University, Benha, Egypt., Kashem R; Bascom Palmer Eye Institute, University of Miami, Miami, FL, United States of America., Abdel-Mottaleb M; Department of Electrical and Computer Engineering, University of Miami, Miami, FL, United States of America., Ozcan E; Bascom Palmer Eye Institute, University of Miami, Miami, FL, United States of America.; Net Eye Medical Center, Gaziantep, Turkey., Tolba M; Bascom Palmer Eye Institute, University of Miami, Miami, FL, United States of America., Cook JC; Bascom Palmer Eye Institute, University of Miami, Miami, FL, United States of America., Parrish RK 2nd; Bascom Palmer Eye Institute, University of Miami, Miami, FL, United States of America.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2020 Oct 14; Vol. 15 (10), pp. e0240509. Date of Electronic Publication: 2020 Oct 14 (Print Publication: 2020).
DOI: 10.1371/journal.pone.0240509
Abstrakt: Purpose: To evaluate see-through Augmented Reality Digital spectacles (AR DSpecs) for improving the mobility of patients with peripheral visual field (VF) losses when tested on a walking track.
Design: Prospective Case Series.
Participants: 21 patients with peripheral VF defects in both eyes, with the physical ability to walk without assistance.
Methods: We developed the AR DSpecs as a wearable VF aid with an augmented reality platform. Image remapping algorithms produced personalized visual augmentation in real time based on the measured binocular VF with the AR DSpecs calibration mode. We tested the device on a walking track to determine if patients could more accurately identify peripheral objects.
Main Outcome Measures: We analyzed walking track scores (number of recognized/avoided objects) and eye tracking data (six gaze parameters) to measure changes in the kinematic and eye scanning behaviors while walking, and assessed a possible placebo effect by deactivating the AR DSpecs remapping algorithms in random trials.
Results: Performance, judged by the object detection scores, improved with the AR DSpecs (P<0.001, Wilcoxon rank sum test) with an average improvement rate of 18.81%. Two gaze parameters improved with the activated algorithm (P<0.01, paired t-test), indicating a more directed gaze on the central path with less eye scanning. Determination of the binocular integrated VF with the DSpecs correlated with the integrated standard automated perimetry (R = 0.86, P<0.001), mean sensitivity difference 0.8 ± 2.25 dB (Bland-Altman).
Conclusions: AR DSpecs may improve walking maneuverability of patients with peripheral VF defects by enhancing detection of objects in a testing environment.
Competing Interests: United States Patent (“Digital Therapeutic Corrective Spectacles“, Patent No. US10386645B2) (MA) and United States Patents (Numbers: US10389989B2, US10409071B2, and US10444514B2) (MA, AS). Patents and PCT are owned by University of Miami and licensed to Horus LLC. MA is an equity holder and sits on the Board of Directors for Horus LLC. This does not alter our adherence to PLOS ONE policies on sharing data and materials.
Databáze: MEDLINE
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