Regenerative Endodontic Therapy in the Management of Immature Necrotic Permanent Dentition: A Systematic Review.

Autor: Alghamdi FT; Department of Oral Biology, Faculty of Dentistry, King AbdulAziz University, Jeddah 80209, Saudi Arabia., Alqurashi AE; Ibn Sina National College for Medical Studies, Dental College, Jeddah 22421, Saudi Arabia.
Jazyk: angličtina
Zdroj: TheScientificWorldJournal [ScientificWorldJournal] 2020 Jul 13; Vol. 2020, pp. 7954357. Date of Electronic Publication: 2020 Jul 13 (Print Publication: 2020).
DOI: 10.1155/2020/7954357
Abstrakt: Materials and Methods: The electronic databases PubMed and Google Scholar were used to search the literature for relevant studies after applying specific inclusion and exclusion criteria. Studies that fulfilled both the inclusion and exclusion criteria were included in this systematic review. The search was conducted by two independent reviewers following the PRISMA guidelines.
Results: Only 46 studies that fulfilled both the inclusion and exclusion criteria, which were conducted within the last 10 years, were included in this systematic review. These studies investigated different aspects of regenerative endodontic therapy including different types of scaffolds, intracanal medications, pulpal space/barriers, root maturation stage, follow-up duration, and updated studies on their use in the management of immature necrotic permanent teeth.
Conclusions: This review concluded the compiled data observed that endodontic regenerative therapy was more efficient in treating immature necrotic permanent teeth and offered a greater advantage that should lead to wider acceptance among endodontists for effective results compared to different treatment options. However, more clinical trials with a standardized protocol and defined clinical, radiographic, and histopathological outcomes with longer follow-up periods are warranted.
Competing Interests: The authors declare that there are no conflicts of interest regarding the publication of this paper.
(Copyright © 2020 Faisal T. Alghamdi and Alaa E. Alqurashi.)
Databáze: MEDLINE
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