COVID-19 outbreak in Jordan: Epidemiological features, clinical characteristics, and laboratory findings.

Autor: Samrah SM; Department of Internal Medicine, Faculty of Medicine, Jordan University of Science and Technology (JUST), Irbid, Jordan., Al-Mistarehi AW; Department of Public Health and Family Medicine, Faculty of Medicine, Jordan University of Science and Technology (JUST), Irbid, Jordan., Ibnian AM; Department of Internal Medicine, Faculty of Medicine, Jordan University of Science and Technology (JUST), Irbid, Jordan., Raffee LA; Department of Accident and Emergency Medicine, Faculty of Medicine, Jordan University of Science and Technology (JUST), Irbid, Jordan., Momany SM; Department of Internal Medicine, Faculty of Medicine, Jordan University of Science and Technology (JUST), Irbid, Jordan., Al-Ali M; Department of Internal Medicine, Faculty of Medicine, Jordan University of Science and Technology (JUST), Irbid, Jordan., Hayajneh WA; Department of Pediatrics and Neonatology, Faculty of Medicine, Jordan University of Science and Technology (JUST), Irbid, Jordan., Yusef DH; Department of Pediatrics and Neonatology, Faculty of Medicine, Jordan University of Science and Technology (JUST), Irbid, Jordan., Awad SM; Department of Pediatrics and Neonatology, Faculty of Medicine, Jordan University of Science and Technology (JUST), Irbid, Jordan., Khassawneh BY; Department of Internal Medicine, Faculty of Medicine, Jordan University of Science and Technology (JUST), Irbid, Jordan.
Jazyk: angličtina
Zdroj: Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2020 Jul 18; Vol. 57, pp. 103-108. Date of Electronic Publication: 2020 Jul 18 (Print Publication: 2020).
DOI: 10.1016/j.amsu.2020.07.020
Abstrakt: Background: In March 2020, an outbreak of coronavirus 19 (COVID-19) was detected in the North of Jordan. This retrospective study is the first from Jordan to report the epidemiologic, clinical, laboratory, and radiologic characteristics of COVID-19 infected patients.
Methods: All patients with laboratory-confirmed COVID-19 infection by RT-PCR in the North of Jordan admitted between March 15 and April 2, 2020 were included. The clinical features, radiological, and laboratory findings were reviewed.
Results: Of 81 patients affected, 79 (97.5%) shared a common exposure to four recent travelers from endemic areas. The mean age was 40 years. Although about half (44 [54.3%]) were females, symptomatic patients were mostly females (75%). The most common presenting symptoms were nasal congestion, sore throat and dry cough. Less than one-third (31%) had chronic diseases. Although 84% of patients reported receiving Bacille Calmette-Guérin (BCG) vaccination, more asymptomatic patients had BCG than symptomatic ( p  = 0.017). Almost all patients (97.5%) had an elevated D-dimer level. Erythrocyte sedimentation rate (ESR) and c-reactive protein were elevated in 50% and 42.7% of patients, respectively. High ESR found to be the predictor of abnormal chest radiograph observed in 13 (16%) patients with OR of 14.26 (95% CI 1.37-147.97, p  = 0.026).
Conclusions: An outbreak of COVID-19 infection in northern Jordan affected more females and relatively young individuals and caused mainly mild illnesses. The strict outbreak response measures applied at early stages probably contributed to the lenient nature of this outbreak, but the contribution of other factors to such variability in COVID-19 presentation is yet to be explained.
Competing Interests: The authors declare that they have no competing interests.
(© 2020 The Author(s).)
Databáze: MEDLINE