Methodological considerations in designing and implementing the harmonized diagnostic assessment of dementia for longitudinal aging study in India (LASI-DAD).

Autor: Banerjee J; Department of Geriatric Medicine, AllIndia Institute of Medical Sciences , New Delhi, India., Jain U; Center for Economic and Social Research, University of Southern California , Los Angeles, California, USA., Khobragade P; Center for Economic and Social Research, University of Southern California , Los Angeles, California, USA., Weerman B; Center for Economic and Social Research, University of Southern California , Los Angeles, California, USA., Hu P; Division of Geriatric Medicine, David Geffen School of Medicine, University of California , Los Angeles, California, USA., Chien S; Center for Economic and Social Research, University of Southern California , Los Angeles, California, USA., Dey S; Department of Geriatric Medicine, AllIndia Institute of Medical Sciences , New Delhi, India., Chatterjee P; Department of Geriatric Medicine, AllIndia Institute of Medical Sciences , New Delhi, India., Saxton J; Department of Neuro- psychiatry, University of Pittsburgh Medical Center , Pittsburgh, Pennsylvania, USA., Keller B; Center for Economic and Social Research, University of Southern California , Los Angeles, California, USA., Crimmins E; Center for Economic and Social Research, University of Southern California , Los Angeles, California, USA., Toga A; Center for Economic and Social Research, University of Southern California , Los Angeles, California, USA., Jain A; Department of Medicine, Dr. SN Medical College , Jodhpur, India., Shanthi GS; Department of Geriatric Medicine, Madras Medical College , Chennai, India., Kurup R; Department of Medicine, Government Medical College , Thiruvananthapuram, India., Raman A; Department of Medicine, Government Medical College , Thiruvananthapuram, India., Chakrabarti SS; Department of Medicine, Institute of Medical Sciences, Banaras Hindu University , Varanasi, India., Varghese M; Department of Psychiatry, National Institute of Mental Health and Neurosciences , Bengaluru, India., John JP; Department of Psychiatry, National Institute of Mental Health and Neurosciences , Bengaluru, India., Joshi H; Department of Psychiatry, National Institute of Mental Health and Neurosciences , Bengaluru, India., Koul P; Department of Internal and pulmonary medicine, Sher-e-Kashmir Institute of Medical Sciences , Srinagar, India., Goswami D; Department of Medicine, Guwahati Medical College , Guwahati, India., Talukdar A; Department of Medicine, Medical College , Kolkata, India., Mohanty RR; Department of Medicine, All India Institute of Medical Sciences , Bhubaneshwar, India., Yadati YSR; Department of Medicine, Nizam's Institute of Medical Sciences , Hyderabad, India., Padmaja M; Department of Medicine, Nizam's Institute of Medical Sciences , Hyderabad, India., Sankhe L; Department of Comunity Medicine, Grant Medical College and J.J. Hospital , Mumbai, India., Pedgaonkar S; Department of Development Studies, International Institute for Population Sciences , Mumbai, India., Arokiasamy P; Department of Development Studies, International Institute for Population Sciences , Mumbai, India., Bloom DE; Department of Global Health and Population, Harvard T.H. Chan School of Public Health , Boston, Massachusetts, USA., Langa K; Department of Internal Medicine, University of Michigan and Veterans Affairs Ann ArborCenter for Clinical Management Research , Ann Arbor, Michigan, USA., Jovicich J; Center for Mind/Brain Sciences, University of Trento , Trento, Italy., Dey AB; Department of Geriatric Medicine, AllIndia Institute of Medical Sciences , New Delhi, India., Lee J; Center for Economic and Social Research, University of Southern California , Los Angeles, California, USA., Gambhir IS; Department of Geriatric Medicine, Institute of Medical Sciences, Banaras Hindu University , Varanasi, India., Rajguru C; Department of Comunity Medicine, Grant Medical College and J.J. Hospital , Mumbai, India.
Jazyk: angličtina
Zdroj: Biodemography and social biology [Biodemography Soc Biol] 2020 Jul-Sep; Vol. 65 (3), pp. 189-213.
DOI: 10.1080/19485565.2020.1730156
Abstrakt: The Harmonized Diagnostic Assessment of Dementia for Longitudinal Aging Study in India (LASI-DAD) is a population-representative, prospective cohort study of late-life cognition and dementia. It is part of an ongoing international research collaboration that aims to measure and understand cognitive impairment and dementia risk by collecting a set of cognitive and neuropsychological assessments and informant reports, referred to as the Harmonized Cognitive Assessment Protocol (HCAP). LASI-DAD provides nationally representative data drawn from a subsample of the ongoing Longitudinal Aging Study in India (LASI). One of LASI-DAD's distinctive features is its rich geriatric assessment, including the collection of venous blood samples and brain imaging data for a subsample of respondents. In this paper, we discuss the methodological considerations of developing and implementing the HCAP protocol in India. The lessons we learned from translating and applying the HCAP protocol in an environment where illiteracy and innumeracy are high will provide important insights to researchers interested in measuring and collecting data on late-life cognition and dementia in developing countries. We further developed an innovative blood management system that enables us to follow the collection, transportation, assay, and storage of samples. Such innovation can benefit other population surveys collecting biomarker data.
Databáze: MEDLINE