Maturity Onset Diabetes of the Young and Generalized Stage III Grade C Periodontitis: A Case Report.

Autor: Chew RJJ; Discipline of Periodontics, Faculty of Dentistry, National University of Singapore, Singapore., Chee HK; Periodontics Unit, Department of Restorative Dentistry, National Dental Centre Singapore, Singapore.
Jazyk: angličtina
Zdroj: Clinical advances in periodontics [Clin Adv Periodontics] 2021 Jun; Vol. 11 (2), pp. 64-69. Date of Electronic Publication: 2020 Aug 13.
DOI: 10.1002/cap.10114
Abstrakt: Introduction: Maturity onset diabetes of the young (MODY) is a rare form of diabetes mellitus resulting from single nucleotide polymorphisms. There is a lack of evidence describing their periodontal condition and the management of these patients. The objective of this case report is to present the 6-month outcomes following non-surgical periodontal treatment of a patient diagnosed with MODY 5, the Renal Cyst and Diabetes Syndrome.
Case Presentation: This case report describes the periodontal presentation and non-surgical management of a 21-year-old patient, diagnosed with hyperglycemia (HbA1c >14%) and stage 4 chronic kidney disease. She presented with generalized severe chronic periodontitis and multiple periodontal abscesses. She was treated with quadrant debridement with adjunctive systemic amoxicillin and metronidazole and 0.2% chlorhexidine mouth rinse. Significant improvement was observed after treatment, remaining stable 6-month post-treatment, with only two sites with probing depths ≥5 mm. This was consistent with a reduction of the periodontal inflamed surface area from 3165 to 500 mm 2 . HbA1c was also reduced to 8.7% 6 months after treatment.
Conclusions: MODY patients presenting with periodontitis can be successfully treated non-surgically, concurrent with diabetic management.
(© 2020 American Academy of Periodontology.)
Databáze: MEDLINE
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