Electroacupuncture for post-stroke overactive bladder: a multi-centre pilot randomized controlled trial.

Autor:	Chen H; School of Chinese Medicine, The University of Hong Kong, Hong Kong, China.; Department of Chinese Medicine, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China., Wang C; Shanghai TCM-integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China., Zhou M; Shanghai TCM-integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China., Yan Chan P; School of Chinese Medicine, The University of Hong Kong, Hong Kong, China., Lo Yam L; School of Chinese Medicine, The University of Hong Kong, Hong Kong, China., Lok Lam W; School of Chinese Medicine, The University of Hong Kong, Hong Kong, China., Leung KP; Rehabilitation Unit, Department of Medicine, Tung Wah Hospital, Hong Kong, China., Li SW; Rehabilitation Unit, Department of Medicine, Tung Wah Hospital, Hong Kong, China., Tsang WY; Department of Geriatrics and Rehabilitative Medicine, Tung Wah Eastern Hospital, Hong Kong, China., Fung-Leung Ng B; The Chinese Medicine Department, Hospital Authority, Hong Kong, China., Tat-Chi Ziea E; The Chinese Medicine Department, Hospital Authority, Hong Kong, China., Yeung WF; School of Nursing, the Hong Kong Polytechnic University, Hong Kong, China., Lao L; School of Chinese Medicine, The University of Hong Kong, Hong Kong, China.; Department of Chinese Medicine, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
Jazyk:	angličtina
Zdroj:	Acupuncture in medicine : journal of the British Medical Acupuncture Society [Acupunct Med] 2021 Jun; Vol. 39 (3), pp. 175-183. Date of Electronic Publication: 2020 Jul 09.
DOI:	10.1177/0964528420925488
Abstrakt:	Background: Although acupuncture has been shown to be effective at treating overactive bladder (OAB) following stroke, to our knowledge, no randomized controlled trial (RCT) examining the effects of acupuncture on patients with post-stroke OAB has been conducted. The aim of this preliminary study was to explore the effects of electroacupuncture (EA) in the treatment of post-stroke OAB. Methods: This study was a multi-site randomized, assessor-blind, controlled pilot trial of patients with post-stroke OAB. In all, 34 post-stroke subjects (mean age: 71.0 years; 32.4% female) with OAB symptoms were randomly assigned to the treatment group or control group in a 1:1 ratio. The subjects in the treatment group were treated with six sessions of EA for 4 weeks, while the subjects in the control group received usual care. The primary outcome measure was the overactive bladder symptom scale (OABSS). Secondary outcome measures included a three day bladder diary and the stroke-specific quality-of-life scale (SSQoL). Results: EA showed a moderate effect size (ES) on the perceived severity of OAB symptoms as measured by the OABSS at week 5 (one week post-treatment, ES 0.57; p = 0.034) and week 8 (three weeks post-treatment, ES 0.60; p = 0.021), although the results did not remain statistically significant after Bonferroni correction for multiple testing. No significant differences in bladder diary parameters or SSQoL score were found. The EA treatment was well tolerated by the post-stroke subjects. Conclusion: A six-session EA treatment was feasible and appeared to reduce OAB symptoms in post-stroke patients. Further fully powered trials are warranted to confirm the efficacy of EA for those with post-stroke OAB.
Databáze:	MEDLINE
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