| Autor: |
De Vincentiis L; Macerata General Hospital, Macerata, Italy., Mariani MP; Macerata General Hospital, Macerata, Italy., Cesinaro AM; University Hospital Modena, Modena, Italy., Dalena AM; University Hospital Modena, Modena, Italy., Ferrara G; Macerata General Hospital, Macerata, Italy. |
| Jazyk: |
angličtina |
| Zdroj: |
International journal of surgical pathology [Int J Surg Pathol] 2021 Apr; Vol. 29 (2), pp. 211-215. Date of Electronic Publication: 2020 Jul 01. |
| DOI: |
10.1177/1066896920937784 |
| Abstrakt: |
Introduction. Previously considered an exceedingly rare entity, sebaceous carcinoma of the breast is now regarded in the World Health Organization 2019 classification as a "special histopathological pattern" of invasive breast carcinoma of no special type. Case Description . In this article, we report the case of a fine needle aspiration cytology and the histopathological features of a breast carcinoma with clear-cut morphological features suggesting sebaceous differentiation, but showing no positive staining with the anti-adipophilin antibody. Conclusions. A morphologically clear-cut sebaceous differentiation is not invariably associated with adipophilin positivity; moreover, in breast carcinoma, adipophilin positivity does not automatically imply sebaceous differentiation. At present, immunomorphological evidence for the recognition of sebaceous carcinoma as a "special type" breast carcinoma subtype is too weak. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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