Autor: |
Xu HN; Department of Anatomy and Physiology, Basic Medical School, Shanghai Jiao Tong University, Shanghai 200025, China., Cai ZZ; Department of Anatomy and Physiology, Basic Medical School, Shanghai Jiao Tong University, Shanghai 200025, China., Wang Y; Department of Anatomy and Physiology, Basic Medical School, Shanghai Jiao Tong University, Shanghai 200025, China., Wu DE; Department of Anatomy and Physiology, Basic Medical School, Shanghai Jiao Tong University, Shanghai 200025, China., Rong WF; Department of Anatomy and Physiology, Basic Medical School, Shanghai Jiao Tong University, Shanghai 200025, China., Zhang GH; Department of Anatomy and Physiology, Basic Medical School, Shanghai Jiao Tong University, Shanghai 200025, China. ghzhang2009@shsmu.edu.cn. |
Abstrakt: |
Interactions among the nervous, the endocrine and the immune systems enable the gut to respond to the dietary products, pathogens and microbiota, which maintains the homeostasis of the body. However, dysbiosis may induce or aggravate the gastrointestinal (GI) and extra-GI diseases through changing the activities of enteric nervous system (ENS), enteroendocrine cells and enteric immune cells. Here we review recent advances in the understandings on how intestinal flora may impact the enteric neuro-endocrine-immune system in the gut, thereby contributing to the regulation of pathophysiological processes. |