Respiratory muscle work influences locomotor convective and diffusive oxygen transport in human heart failure during exercise.
Autor: | Smith JR; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA., Berg JD; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA., Curry TB; Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA., Joyner MJ; Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA., Olson TP; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA. |
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Jazyk: | angličtina |
Zdroj: | Physiological reports [Physiol Rep] 2020 Jun; Vol. 8 (12), pp. e14484. |
DOI: | 10.14814/phy2.14484 |
Abstrakt: | Introduction: It remains unclear if naturally occurring respiratory muscle (RM) work influences leg diffusive O Methods: Ten HFrEF patients and 10 healthy control matched participants performed two submaximal exercise bouts (i.e., with and without RM unloading). During exercise, leg blood flow was measured via constant infusion thermodilution. Intrathoracic pressure was measured via esophageal balloon. Radial arterial and femoral venous blood gases were measured and used to calculate leg arterial and venous content (CaO Results: From CTL to RM unloading, leg VO Conclusion: Our data suggest RM unloading leads to increased leg VO (© 2020 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.) |
Databáze: | MEDLINE |
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