Caspase-8 and FADD: Where Cell Death and Inflammation Collide.
| Autor: | Amaral MP; Center for Cellular and Molecular Therapy (CTCMol), Federal University of São Paulo (UNIFESP), São Paulo, Brazil., Bortoluci KR; Center for Cellular and Molecular Therapy (CTCMol), Federal University of São Paulo (UNIFESP), São Paulo, Brazil. Electronic address: kbortoluci@gmail.com. |
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| Jazyk: | angličtina |
| Zdroj: | Immunity [Immunity] 2020 Jun 16; Vol. 52 (6), pp. 890-892. |
| DOI: | 10.1016/j.immuni.2020.05.008 |
| Abstrakt: | Caspase-8 is a master regulator of cell death pathways, although its regulation during inflammation remains elusive. Using elegant mouse genetic approaches, Schwarzer et al. and Tummers et al. revealed the importance of FADD in regulating caspase-8-mediated inflammatory responses and gut homeostasis. (Copyright © 2020 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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