Sex Differences of Migraine: Results of a Nationwide Home-based Study in Turkey.

Autor: Akarsu EO; Department of Neurology, Uludağ University, Uludağ School of Medicine, Bursa, Turkey., Baykan B; Department of Neurology, İstanbul University, İstanbul Faculty of Medicine, İstanbul, Turkey., Ertaş M; Department of Neurology, İstanbul University, İstanbul Faculty of Medicine, İstanbul, Turkey., Zarifoğlu M; Department of Neurology, Uludağ University, Uludağ School of Medicine, Bursa, Turkey., Kocasoy Orhan E; Department of Neurology, İstanbul University, İstanbul Faculty of Medicine, İstanbul, Turkey., Saip S; Department of Neurology, İstanbul University, Cerrahpaşa School of Medicine, İstanbul, Turkey., Siva A; Department of Neurology, İstanbul University, Cerrahpaşa School of Medicine, İstanbul, Turkey., Önal AE; Department of Community Health, İstanbul University, İstanbul Faculty of Medicine, İstanbul, Turkey., Karli N; Department of Neurology, Uludağ University, Uludağ School of Medicine, Bursa, Turkey.
Jazyk: angličtina
Zdroj: Noro psikiyatri arsivi [Noro Psikiyatr Ars] 2019 Sep 26; Vol. 57 (2), pp. 126-130. Date of Electronic Publication: 2019 Sep 26 (Print Publication: 2020).
DOI: 10.29399/npa.23240
Abstrakt: Introduction: The prevalence of migraine was found to be more than three-fold higher in women as compared with men, and in addition to differences in prevalence rates, the characteristics and associated features might also differ between the sexes. The aim of this study was to compare sex-specific features of migraine and demographic parameters in a nationwide population-based study in Turkey.
Methods: Among 5323 subjects, a total of 871 patients who were diagnosed as having definite migraine according to the diagnostic criteria of the International Classification of Headache Disorders-III (ICHD-III) were included in our study. The demographic characteristics, associated features, and triggers of migraine were examined with regard to sex.
Results: The study group comprised 640 women (73.5%) and 231 men (26.5%), with a female to male ratio of 2.8:1. Attack duration, mean migraine disability assessment scores (MIDAS), frequencies of nausea, vomiting, osmophobia, vertigo/dizziness, and allodynia were found significantly different between women and men. When we compared these parameters between men and postmenopausal women, all these parameters were still significant except nausea. Odor was statistically more frequent as a reported trigger in women, whereas excessive sleep was a statistically more frequent triggering factor in men. The rates of depression and allergy were significantly higher in women when compared with men.
Conclusion: Longer attack duration, higher MIDAS scores, and the frequencies of nausea, vomiting, osmophobia, vertigo/dizziness, and allodynia were more significant in women and this variance in sex persisted after menopause. Also, some trigger factors and co-morbidities differed between the sexes. These findings might result from complex genetic factors besides sociocultural influences, biologic, and sociocultural roles. Future studies should continue to explore biologic and genetic factors with respect to sex in migraine.
Competing Interests: Conflict of Interest: No conflict of interest was declared by the authors.
(Copyright: © 2020 Turkish Neuropsychiatric Society.)
Databáze: MEDLINE
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