Intracranial Ewing Sarcoma - A case report.

Autor:	Huang J; Department of Neurosurgery, St. George Public Hospital, Kogarah, New South Wales, Australia., Ghent F; Department of Neurosurgery, St. George Public Hospital, Kogarah, New South Wales, Australia., Levingston R; Department of Neurosurgery, St. George Public Hospital, Kogarah, New South Wales, Australia., Scholsem M; Department of Neurosurgery, St. George Public Hospital, Kogarah, New South Wales, Australia.
Jazyk:	angličtina
Zdroj:	Surgical neurology international [Surg Neurol Int] 2020 May 30; Vol. 11, pp. 134. Date of Electronic Publication: 2020 May 30 (Print Publication: 2020).
DOI:	10.25259/SNI_178_2020
Abstrakt:	Background: Intracranial Ewing's sarcoma (ES) is a rare entity with <15 cases reported in the literature. It belongs to a family of round-cell neuroectodermally derived tumors bearing many similarities to peripheral primitive neuroectodermal tumor (pPNET). There is currently no established treatment protocol. Reported cases are treated with either surgery alone or surgery with adjuvant chemotherapy and radiation. Case Description: We describe a case of intracranial left frontal ES in a 19-year-old patient who presented with change in behavior. Diagnosis was unclear based on radiological findings on MRI and CT alone. MRI brain with contrast demonstrated a large extra-axial ovoid heterogeneously enhancing left frontal convexity mass. The patient underwent gross total resection with adjuvant chemotherapy and radiation. No local or systemic recurrence was found at 12 months postoperatively. Conclusion: Intracranial ES/pPNET is rare tumor with nonspecific clinical presentation and radiological findings. They are locally invasive. Surgery with adjuvant chemoradiation is the mainstay treatment. Distinction of pPNET and cPNET is important for therapeutic and prognostic purposes. Competing Interests: There are no conflicts of interest. (Copyright: © 2020 Surgical Neurology International.)
Databáze:	MEDLINE
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